Horne Katie S, Kunkle Gail A
Department of Small Animal Clinical Science, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
J Feline Med Surg. 2009 Aug;11(8):627-32. doi: 10.1016/j.jfms.2008.10.008. Epub 2009 Feb 6.
Cutaneous infection caused by rapidly growing mycobacteria is a relatively uncommon condition in cats, with variable response rates to surgical debulking and aggressive antibiotic therapy. To date, there have been very few case reports of this disease, especially in the United States. This study reviews a series of cases of cats with rapidly growing cutaneous mycobacterial infections from the south-eastern United States. A majority of the cats were spayed female domestic shorthairs. The median age at onset of clinical signs was 8 years. A majority of cats presented with characteristic lesions in multiple locations, and half of the cats had a known incidence of trauma preceding the development of clinical signs. Mycobacterium fortuitum was the most frequently cultured organism. Cats were treated with a variety of antibiotics for a median of 12 months, and half of them underwent surgical debulking of infected tissue. Five out of the 10 cats reached clinical resolution, while five did not. Those that did resolve required a median of 7 months of antibiotic treatment following diagnosis, and had been lesion-free for a median of 24 months at the time this study was completed. Those that did not resolve were treated for a median of 20 months following diagnosis, two of which were still being treated at the time this study was completed.
由快速生长分枝杆菌引起的皮肤感染在猫中是一种相对不常见的病症,对手术减瘤和积极的抗生素治疗的反应率各不相同。迄今为止,关于这种疾病的病例报告非常少,尤其是在美国。本研究回顾了一系列来自美国东南部患有快速生长的皮肤分枝杆菌感染的猫的病例。大多数猫是已绝育的雌性家猫短毛猫。出现临床症状的中位年龄为8岁。大多数猫在多个部位出现特征性病变,并且一半的猫在临床症状出现之前有已知的创伤发生率。偶然分枝杆菌是最常培养出的病原体。猫接受了多种抗生素治疗,中位治疗时间为12个月,其中一半接受了感染组织的手术减瘤。10只猫中有5只达到临床治愈,而5只没有。那些治愈的猫在诊断后中位需要7个月的抗生素治疗,并且在本研究完成时无病变的中位时间为24个月。那些未治愈的猫在诊断后中位接受了20个月的治疗,其中两只在本研究完成时仍在接受治疗。