Holland C T, Canfield P J, Watson A D, Allan G S
Department of Veterinary Anatomy, University of Sydney, NSW, Australia.
J Vet Intern Med. 1991 May-Jun;5(3):151-9. doi: 10.1111/j.1939-1676.1991.tb00942.x.
A polysystemic disorder was observed in three related English Springer Spaniel dogs that demonstrated regurgitation from an early age, slowly progressive temporal muscle atrophy with partial trismus, and less pronounced generalized skeletal muscle atrophy. All dogs exhibited moderate dyserythropoietic anemia, polymyopathy with megaesophagus, and varying degrees of cardiomegaly. The prevalence, etiology, underlying pathomechanism, and possible mode of inheritance remain to be elucidated.
在三只相关的英国激飞猎犬中观察到一种多系统疾病，这些犬从幼年起就出现反流，颞肌进行性缓慢萎缩并伴有部分牙关紧闭，以及不太明显的全身性骨骼肌萎缩。所有犬均表现出中度的发育异常性贫血、伴有巨食管的多肌病以及不同程度的心脏肥大。其患病率、病因、潜在发病机制和可能的遗传方式仍有待阐明。
