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使用尿雌酮结合物测定法检测食蟹猕猴(Macaca fascicularis)的最佳交配时间。

The use of a urinary estrone conjugates assay for detection of optimal mating time in the cynomolgus macaque (Macaca fascicularis).

作者信息

Behboodi E, Katz D F, Samuels S J, Tell L, Hendrickx A G, Lasley B L

机构信息

Department of Obstetrics and Gynecology, University of California, Davis 95616.

出版信息

J Med Primatol. 1991 Jul;20(5):229-34.

PMID:1920378
Abstract

Forty-four female cynomolgus macaques (Macaca fascicularis) were examined to determine the optimum fertile period for mating. Daily urinary estrone conjugates (E1C) were measured, beginning on day 7 of the menstrual cycle, until a 1.5-gold E1C rise above the baseline was detected. The females were bred the next morning. Pregnancies were verified in all animals at day 18 postbreeding, and/or on day 25 postbreeding. Serum progesterone levels were used to correlate the relationship between ovulation and the E1C peak. Forty-four of the 57 cycles indicated a urinary E1C peak between days 10-15 of the menstrual cycle; this peak occurred on the day following the initial 1.5-fold to twofold rise in 90% of the cycles. A single 2-hr mating period the day before, the day of, or the day after the E1C peak resulted in conception in 17 of 44 (38.6%) animals.

摘要

对44只雌性食蟹猴(猕猴属)进行检查,以确定最佳受孕交配期。从月经周期的第7天开始测量每日尿雌酮结合物(E1C),直至检测到E1C比基线升高1.5倍。次日早晨让雌性进行交配。在交配后第18天和/或第25天对所有动物进行妊娠检查。使用血清孕酮水平来关联排卵与E1C峰值之间的关系。57个周期中的44个显示月经周期第10 - 15天出现尿E1C峰值;在90%的周期中,该峰值出现在E1C最初升高1.5倍至两倍后的第二天。在E1C峰值前一天、当天或后一天进行单次2小时的交配期,44只动物中有17只(38.6%)受孕。

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