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紫杉醇联合卡铂化疗治疗妊娠合并卵巢黏液性囊腺癌

Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy.

机构信息

Department of Obstetrics and Gynecology, Musashikosugi Hospital, Nippon Medical School, 1-396 Kosugitchou, Nakaharaku, Kawasaki, Kanagawa, 211-0063, Japan.

出版信息

Arch Gynecol Obstet. 2009 Oct;280(4):633-6. doi: 10.1007/s00404-009-0950-2. Epub 2009 Feb 11.

Abstract

Combined chemotherapy using carboplatin and paclitaxel has been established as a standard regimen for epithelial ovarian carcinoma. We present the case of a 36-year-old woman with ovarian mucinous cystadenocarcinoma who underwent exploratory laparotomy during pregnancy, revealing Stage 1c at gestational week 15. Afterwards, five courses of paclitaxel and carboplatin chemotherapy were administered biweekly from gestational week 24. Cesarean section was performed at gestational week 36. No recurrent or metastatic lesions were found and outcomes for both mother and neonate have been satisfactory for 40 months since diagnosis of ovarian carcinoma.

摘要

联合化疗使用卡铂和紫杉醇已经成为上皮性卵巢癌的标准治疗方案。我们报告了 1 例 36 岁的卵巢黏液性囊腺癌患者,该患者在妊娠期间接受了剖腹探查术,在妊娠 15 周时发现为 1c 期。随后,从妊娠 24 周开始,每两周接受 5 个疗程的紫杉醇和卡铂化疗。在妊娠 36 周时进行了剖宫产。未发现复发病灶或转移灶,自诊断为卵巢癌以来,母亲和新生儿的情况已经令人满意 40 个月。

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