Turner A
The Medical Centre, Grand Falls, Newfoundland, Canada.
J Otolaryngol. 1991 Aug;20(4):274-5.
Wegener's granulomatosis can be a difficult diagnosis to establish. It is not uncommon to require repeated biopsies over many months for histologic confirmation. A recently developed seromarker--anti-neutrophil cytoplasm antibody--ANCA (synonymous with anticytoplasmic autoantibody--ACPA) adds a new and valuable tool for diagnosis. The literature shows this to be a highly specific and sensitive test for Wegener's granulomatosis.
韦格纳肉芽肿病的诊断可能颇具难度。通常需要在数月内反复进行活检以获得组织学确诊。一种新研发的血清标志物——抗中性粒细胞胞浆抗体（ANCA，与抗胞浆自身抗体——ACPA同义）为诊断增添了一项新的有价值工具。文献表明，这是一项针对韦格纳肉芽肿病的高度特异且敏感的检测。
