Mycoses. 2010 Jan;53(1):89-92. doi: 10.1111/j.1439-0507.2008.01672.x. Epub 2009 Feb 3.
We report two cases of invasive zygomycoses occurring in severely immunocompromised patients with haematological malignancies that were successfully treated with liposomal amphotericin B and surgical debridement, followed by oral administration of posaconazole. These cases demonstrated that an early instituted, aggressive and combined therapeutic approach results in a recovery from invasive fungal infection, without any relapse of infection, thanks to secondary prophylaxis using posaconazole.
我们报告了两例侵袭性曲霉菌病发生在严重免疫功能低下的血液病恶性肿瘤患者，他们成功地接受了脂质体两性霉素 B 和手术清创治疗，随后口服泊沙康唑。这些病例表明，早期采用积极的联合治疗方法可使患者从侵袭性真菌感染中康复，由于使用泊沙康唑进行二级预防，没有任何感染复发。
