Wada H, Minamikawa K, Ohiwa M, Kaneko T, Mori Y, Tamaki S, Takagi M, Kageyama S, Katayama N, Minami N
2nd Department of Internal Medicine, Mie University School of Medicine.
Rinsho Ketsueki. 1991 Jul;32(7):773-6.
Plasma Interleukin-6 (IL-6) level was measured in patients with idiopathic thrombocytopenic purpura (ITP), systemic lupus erythematosus (SLE), rheumatoid arthritis and aplastic anemia. Increase in the plasma level of IL-6 was observed in patients with ITP and SLE. The plasma IL-6 level decreased with progression of the treatment for ITP, and it showed weak negative correlations with the platelet count at the onset of ITP. The increases in the plasma IL-6 level suggest the involvement of activation of the immune system in the pathogenesis of ITP.
对特发性血小板减少性紫癜（ITP）、系统性红斑狼疮（SLE）、类风湿性关节炎和再生障碍性贫血患者测定血浆白细胞介素-6（IL-6）水平。观察到ITP和SLE患者血浆IL-6水平升高。ITP患者治疗过程中血浆IL-6水平下降，且与ITP发病时的血小板计数呈弱负相关。血浆IL-6水平升高提示免疫系统激活参与ITP发病机制。
