Nishi K, Yamada M, Morishita D, Nakamura Y, Murata Y, Fujioka M, Muramoto S, Murakami S, Sasaki K, Yasui M
Department of Internal Medicine, Noto General Hospital, Nanao.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Jul;29(7):904-8.
A rare case of a 25-year-old man with pulmonary aspergillosis is reported. Pulmonary bulla and eosinophilic pneumonia in the right upper lobe were diagnosed by chest roentgenogram and transbronchial lung biopsy. Because the patient developed infective bullae during steroid therapy, we performed transcutaneous thoracic drainage and right upper lobectomy. The resected lung tissue contained numerous hyphae of Aspergillus. Around the hyphae of Aspergillus, granulomatous reaction and eosinophilic infiltration were observed. Antibodies against Aspergillus were detected in the serum of the patient. The number of peripheral blood eosinophils decreased after right upper lobectomy. These findings suggest that pulmonary bullae and eosinophilic pneumonia may be a rare manifestation of pulmonary aspergillosis.
报告了一例25岁男性肺曲霉病罕见病例。通过胸部X线片和经支气管肺活检诊断为右上叶肺大疱和嗜酸性粒细胞性肺炎。由于患者在类固醇治疗期间出现感染性肺大疱，我们进行了经皮胸腔引流和右上叶切除术。切除的肺组织中含有大量曲霉菌丝。在曲霉菌丝周围，观察到肉芽肿反应和嗜酸性粒细胞浸润。在患者血清中检测到抗曲霉菌抗体。右上叶切除术后外周血嗜酸性粒细胞数量减少。这些发现表明，肺大疱和嗜酸性粒细胞性肺炎可能是肺曲霉病的一种罕见表现。
