Mollon Brent, Chong Jaron, Holbrook Anne M, Sung Melani, Thabane Lehana, Foster Gary
The Centre for Evaluation of Medicines, McMaster University, Hamilton, Ontario, Canada.
BMC Med Inform Decis Mak. 2009 Feb 11;9:11. doi: 10.1186/1472-6947-9-11.
Computerized decision support systems (CDSS) are believed to have the potential to improve the quality of health care delivery, although results from high quality studies have been mixed. We conducted a systematic review to evaluate whether certain features of prescribing decision support systems (RxCDSS) predict successful implementation, change in provider behaviour, and change in patient outcomes.
A literature search of Medline, EMBASE, CINAHL and INSPEC databases (earliest entry to June 2008) was conducted to identify randomized controlled trials involving RxCDSS. Each citation was independently assessed by two reviewers for outcomes and 28 predefined system features. Statistical analysis of associations between system features and success of outcomes was planned.
Of 4534 citations returned by the search, 41 met the inclusion criteria. Of these, 37 reported successful system implementations, 25 reported success at changing health care provider behaviour, and 5 noted improvements in patient outcomes. A mean of 17 features per study were mentioned. The statistical analysis could not be completed due primarily to the small number of studies and lack of diversity of outcomes. Descriptive analysis did not confirm any feature to be more prevalent in successful trials relative to unsuccessful ones for implementation, provider behaviour or patient outcomes.
While RxCDSSs have the potential to change health care provider behaviour, very few high quality studies show improvement in patient outcomes. Furthermore, the features of the RxCDSS associated with success (or failure) are poorly described, thus making it difficult for system design and implementation to improve.
尽管高质量研究的结果参差不齐,但计算机化决策支持系统(CDSS)被认为有提高医疗服务质量的潜力。我们进行了一项系统评价,以评估处方决策支持系统(RxCDSS)的某些特征是否能预测成功实施、医疗服务提供者行为的改变以及患者结局的改变。
对Medline、EMBASE、CINAHL和INSPEC数据库(最早记录至2008年6月)进行文献检索,以识别涉及RxCDSS的随机对照试验。两名评审员独立评估每篇文献的结局和28个预先定义的系统特征。计划对系统特征与结局成功之间的关联进行统计分析。
检索返回的4534篇文献中,41篇符合纳入标准。其中,37篇报告了系统的成功实施,25篇报告了在改变医疗服务提供者行为方面取得成功,5篇指出患者结局有所改善。每项研究平均提及17个特征。由于研究数量少且结局缺乏多样性,无法完成统计分析。描述性分析未证实相对于未成功的试验,在成功的试验中,对于实施、医疗服务提供者行为或患者结局而言,有任何特征更为普遍。
虽然RxCDSS有改变医疗服务提供者行为的潜力,但很少有高质量研究表明患者结局有所改善。此外,与成功(或失败)相关的RxCDSS特征描述欠佳,因此系统设计和实施难以改进。