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本文引用的文献

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Development of a single detector ring micro crystal element scanner: QuickPET II.单探测器环微晶元扫描仪QuickPET II的研发
Mol Imaging. 2005 Apr-Jun;4(2):117-27. doi: 10.1162/15353500200504154.
2
Pragmatic fully 3D image reconstruction for the MiCES mouse imaging PET scanner.用于MiCES小鼠成像PET扫描仪的实用全3D图像重建
Phys Med Biol. 2004 Oct 7;49(19):4563-78. doi: 10.1088/0031-9155/49/19/008.

用于正电子发射断层扫描(PET)扫描仪的深度交互探测器设计dMiCE的新方向。

New Directions for dMiCE - a Depth-of-Interaction Detector Design for PET Scanners.

作者信息

Lewellen T K, Macdonald L R, Miyaoka R S, McDougald W, Champley K

出版信息

IEEE Nucl Sci Symp Conf Rec (1997). 2007;5:3798-3802. doi: 10.1109/NSSMIC.2007.4436948.

DOI:10.1109/NSSMIC.2007.4436948
PMID:19212455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2638085/
Abstract

Our laboratory has been developing a depth-of-interaction (DOI) detector design based on light sharing between pairs or quadlets of crystals. Work to date has been utilizing 2×2 mm cross section crystals carefully positioned on a multi-anode PMT. However, there is still significant light sharing in the PMT glass envelope and current PMT designs do not allow one-on-one coupling for arrays of smaller cross section crystals. One-on-one coupling is optimal for implementing the DOI estimator. An alternative to PMTs is to take advantage of progress in fabrication of metal resistive-layer semiconductor photodetectors to provide arrays with one-on-one crystal coupling. We report on our initial tests of one manufacturer's devices. The photodetector (MAPD) and scintillator combination (LFS-3) are both products of Zecotek. The LFS-3 crystal is a variant of LFS that has a better spectral match to the MAPD. Measurements show performance equivalent to or better than that obtained with PMTs and LSO, LFS, or LYSO crystals. For example, 2×2×20 mm crystals are providing 11% energy resolution. The high gain of such devices allow flexibility in designs for both the array and the supporting electronics. We are proceeding with the dMiCE development based on the use of MAPD and LFS-3 arrays.

摘要

我们实验室一直在研发一种基于晶体对或四重晶体之间光共享的相互作用深度(DOI)探测器设计。迄今为止的工作一直使用精心放置在多阳极光电倍增管(PMT)上的2×2毫米横截面晶体。然而,在PMT玻璃外壳中仍存在大量的光共享,并且当前的PMT设计不允许对较小横截面晶体阵列进行一对一耦合。一对一耦合对于实现DOI估计器是最佳的。光电倍增管的一种替代方案是利用金属电阻层半导体光电探测器制造方面的进展,以提供具有一对一晶体耦合的阵列。我们报告了对一家制造商的器件的初步测试情况。光电探测器(MAPD)和闪烁体组合(LFS-3)均为Zecotek公司的产品。LFS-3晶体是LFS的一种变体,它与MAPD具有更好的光谱匹配。测量结果表明,其性能等同于或优于使用光电倍增管以及LSO、LFS或LYSO晶体所获得的性能。例如,2×2×20毫米的晶体实现了11%的能量分辨率。此类器件的高增益使得阵列和支持电子设备的设计具有灵活性。我们正在基于MAPD和LFS-3阵列推进dMiCE的研发工作。