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病例报告:植入三年后人骨骺移植的组织学研究。

Case report: histologic study of a human epiphyseal transplant at 3 years after implantation.

作者信息

Sales de Gauzy J, Accadbled F, Gomez Brouchet A, Abid A

机构信息

Department of Pediatric Orthopaedic Surgery, Hôpital des Enfants, Toulouse, France.

出版信息

Clin Orthop Relat Res. 2009 Jul;467(7):1915-20. doi: 10.1007/s11999-009-0723-z. Epub 2009 Feb 11.

DOI:10.1007/s11999-009-0723-z
PMID:19212796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2690745/
Abstract

A 5-year-old boy underwent surgical excision of a Ewing's sarcoma of the proximal femur. Reconstruction was performed using an ipsilateral vascularized epiphyseal transplant and a femoral allograft. Local recurrence of the tumor necessitated hip disarticulation 3 years after the initial procedure. We then performed a histologic analysis of the transplant. The growth plate was still normal in structure but had richly vascularized hyperplastic layers. We observed bridging between the articular cartilage and the growth plate.

摘要

一名5岁男孩接受了股骨近端尤因肉瘤的手术切除。使用同侧带血管骨骺移植和同种异体股骨进行重建。初始手术后3年,肿瘤局部复发,需要进行髋关节离断术。然后我们对移植组织进行了组织学分析。生长板结构仍正常,但有血管丰富的增生层。我们观察到关节软骨和生长板之间有桥接。

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本文引用的文献

1
Vascular basis of free transfer of proximal epiphysis and diaphysis of fibula: an anatomical study.腓骨近端骨骺与骨干游离移植的血管基础:一项解剖学研究。
Arch Orthop Trauma Surg. 2009 Feb;129(2):183-7. doi: 10.1007/s00402-008-0600-3. Epub 2008 Feb 29.
2
Vascularized epiphyseal transplant.带血管蒂骨骺移植
Orthop Clin North Am. 2007 Jan;38(1):95-101, vii. doi: 10.1016/j.ocl.2006.10.003.
3
Epiphyseal transplant: harvesting technique of the proximal fibula based on the anterior tibial artery.骨骺移植:基于胫前动脉的腓骨近端采集技术。
Microsurgery. 2005;25(4):284-92. doi: 10.1002/micr.20130.
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Vascularized proximal fibular epiphyseal transfer for distal radial reconstruction.带血管蒂近端腓骨骨骺转移用于桡骨远端重建。
J Bone Joint Surg Am. 2004 Jul;86(7):1504-11. doi: 10.2106/00004623-200407000-00021.
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Original biological reconstruction of the hip in a 4-year-old girl.一名4岁女孩髋关节的原始生物重建。
Lancet. 2003 Jan 11;361(9352):140-2. doi: 10.1016/S0140-6736(03)12192-7.
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Skeletal reconstruction with a free vascularized fibula graft associated to bone allograft after resection of malignant bone tumor of limbs.肢体恶性骨肿瘤切除术后采用游离带血管腓骨移植联合同种异体骨进行骨骼重建。
Handchir Mikrochir Plast Chir. 2001 Jul;33(4):277-82. doi: 10.1055/s-2001-16597.
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Free vascularized growth-plate transfer after bone tumor resection in children.儿童骨肿瘤切除术后的带血管游离生长板移植
J Reconstr Microsurg. 1998 Feb;14(2):137-43. doi: 10.1055/s-2007-1000157.
8
Growth of the proximal fibular physis and remodeling of the epiphysis after microvascular transfer. A case report.微血管转移术后腓骨近端骨骺生长及骨骺重塑。一例报告。
J Bone Joint Surg Am. 1997 Apr;79(4):583-6.
9
Epiphysial growth after free fibular transfer with and without microvascular anastomosis. Experimental study in the dog.游离腓骨移植伴或不伴微血管吻合后的骨骺生长。犬实验研究。
J Bone Joint Surg Br. 1983 Aug;65(4):493-501. doi: 10.1302/0301-620X.65B4.6874722.
10
Free microvascular epiphyseal-plate transplantation. An experimental study in dogs.游离微血管骺板移植。犬实验研究。
J Bone Joint Surg Am. 1984 Dec;66(9):1421-30.