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[同时携带爱泼斯坦 - 巴尔病毒和巨细胞病毒基因组的人淋巴母细胞系中的免疫球蛋白和绵羊红细胞受体]

[Immunoglobulins and sheep red cell receptors in human lymphoblastoid cell lines simultaneously carrying Epstein-Barr virus and cytomegalovirus genomes].

作者信息

Bourkas A E, Okada W, Menezes J, Joncas J H

出版信息

Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):215-7.

PMID:192131
Abstract

In this communication we attempt to characterize the principal immunological properties of 3 human lymphoblastoid cell lines (LCL) established in our laboratory which carry both the EBV and CMV genomes. The data obtained suggests that two LCL are representative of B lymphocytes while the other LCL has a mixed cell population with the majority being of the B type. The reasons for this heterogeneity are discussed. It is suggested that CMV may also transform thymus-independent (B) lymphocytes.

摘要

在本交流中,我们试图描述在我们实验室建立的3种携带EB病毒和巨细胞病毒基因组的人淋巴母细胞系(LCL)的主要免疫学特性。所获得的数据表明,两种LCL代表B淋巴细胞,而另一种LCL具有混合细胞群体,其中大多数为B型。讨论了这种异质性的原因。有人提出,巨细胞病毒也可能转化非胸腺依赖性(B)淋巴细胞。

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