Bourkas A E, Okada W, Menezes J, Joncas J H
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):215-7.
In this communication we attempt to characterize the principal immunological properties of 3 human lymphoblastoid cell lines (LCL) established in our laboratory which carry both the EBV and CMV genomes. The data obtained suggests that two LCL are representative of B lymphocytes while the other LCL has a mixed cell population with the majority being of the B type. The reasons for this heterogeneity are discussed. It is suggested that CMV may also transform thymus-independent (B) lymphocytes.
在本交流中,我们试图描述在我们实验室建立的3种携带EB病毒和巨细胞病毒基因组的人淋巴母细胞系(LCL)的主要免疫学特性。所获得的数据表明,两种LCL代表B淋巴细胞,而另一种LCL具有混合细胞群体,其中大多数为B型。讨论了这种异质性的原因。有人提出,巨细胞病毒也可能转化非胸腺依赖性(B)淋巴细胞。