爱泼斯坦-巴尔病毒（EBV）转化的淋巴母细胞系（LCL）作为混合淋巴细胞培养（MLC）中的刺激细胞。
The Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (LCL) as stimulating cells in mixed lymphocyte culture (MLC).
作者信息
Wasik M, Matej H, Duś D, Myc A
出版信息
Arch Immunol Ther Exp (Warsz). 1983;31(6):879-85.
The MLC response of normal lymphocytes to different kinds of EBV-transformed LCL was investigated. The response to allogeneic LCL cells remarkably exceeded the response to xenogeneic and autologous LCL cells. Stimulation performed with EBV-transformed and normal cells obtained from the same donors showed a correlation in the reaction levels (Q = 0.434). This incomplete correlation was not improved by the reduction of the number of stimulating LCL cells. In MLC stimulated with LCL no statistically significant differences between responses to 2,1 or alloantigens were found.
研究了正常淋巴细胞对不同种类EBV转化的LCL的混合淋巴细胞反应（MLC）。对同种异体LCL细胞的反应明显超过对异种和自体LCL细胞的反应。用来自相同供体的EBV转化细胞和正常细胞进行刺激，反应水平之间存在相关性（Q = 0.434）。减少刺激LCL细胞的数量并没有改善这种不完全相关性。在用LCL刺激的MLC中，对2,1或同种异体抗原的反应之间未发现统计学上的显著差异。
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