Rosmarin David, LaRaia Anne, Schlauder Scott, Gottlieb Alice B
Tufts Medical Center, Tufts University School of Medicine, Department of Dermatology, Boston, MA, USA.
J Drugs Dermatol. 2009 Feb;8(2):169-71.
A 61-year-old female with a 4-year history of disseminated granuloma annulare was successfully treated with the antitumor necrosis factor (TNF)-alpha antibody, adalimumab. The patient had failed high potency topical glucocorticoids, hydroxychloroquine, and narrow-band ultraviolet light (UV)-B phototherapy. Anti-TNF-alpha therapy may be a therapeutic option in patients with disseminated granuloma annulare poorly controlled with conventional medications.
一名患有播散性环状肉芽肿4年的61岁女性，使用抗肿瘤坏死因子（TNF）-α抗体阿达木单抗成功治愈。该患者使用高效外用糖皮质激素、羟氯喹和窄谱紫外线（UV）-B光疗均无效。对于使用传统药物控制不佳的播散性环状肉芽肿患者，抗TNF-α治疗可能是一种治疗选择。
