Kweifio-Okai G
Department of Anatomy and Physiology, Phillip Institute of Technology, Bundoora, Victoria, Australia.
J Ethnopharmacol. 1991 Jul;33(3):263-7. doi: 10.1016/0378-8741(91)90087-t.
A boiling water extract from a powdered sample containing Alstonia boonei root bark (90%) Rauvolfia vomitoria root bark (5%) and Elaeis guineensis nut without pericarp (5%) was tested intraperitoneally for its antiinflammatory activity by measuring rat hindpaw edema induced by the subplantar injection of carrageenin in the presence or absence of arachidonic acid. Arachidonic acid increased swelling during the early phase of carrageenin edema. The extract suppressed the late phase of carrageenin edema and both phases in the presence of arachidonic acid. These preliminary results are consistent with a herbal preparation known to be used in the management of rheumatoid arthritis.
对一份粉末状样品的沸水提取物进行了腹腔注射测试，该样品包含90%的非洲鸡骨常山树皮、5%的催吐萝芙木树皮和5%的无果皮油棕果。通过测量在有或没有花生四烯酸存在的情况下，角叉菜胶足底注射诱导的大鼠后爪水肿，来检测其抗炎活性。花生四烯酸在角叉菜胶水肿的早期阶段会增加肿胀。该提取物抑制了角叉菜胶水肿的后期阶段以及在花生四烯酸存在时的两个阶段。这些初步结果与一种已知用于治疗类风湿性关节炎的草药制剂相符。
