Vitums V C, Edwards M J, Niles N R, Borman J O, Lowry R D
Arch Environ Health. 1977 Mar-Apr;32(2):62-8. doi: 10.1080/00039896.1977.10667257.
After prolonged occupation exposure to amorphous silica dust-a product of vaporized crystalline silica (quartz)-eleven out of forty workers showed reticular and/or nodular abnormalities in roentgenograms of the chest. From this group, we present three illustrative cases. These had widespread pulmonary disease with granulomatous nodules and fibrosis (documented histologically in two cases), but there was no demonstrable restrictive impairment of pulmonary function. We discuss the possible importance of this previously underestimated toxicity, especially in an industrial setting.
在长期职业接触无定形二氧化硅粉尘（一种汽化结晶二氧化硅（石英）的产物）后，40名工人中有11人胸部X线片显示网状和/或结节状异常。在这组病例中，我们展示三个具有代表性的病例。这些病例患有广泛的肺部疾病，伴有肉芽肿性结节和纤维化（两例有组织学记录），但未发现明显的肺功能限制性损害。我们讨论了这种先前被低估的毒性的可能重要性，尤其是在工业环境中。
