Sabattini M S, Daffner J F, Monath T P, Bianchi T I, Cropp C B, Mitchell C J, Aviles G
Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Buenos Aires.
Medicina (B Aires). 1991;51(1):3-8.
In 1981, a localized epizootic of Eastern Equine Encephalitis (EEE) occurred in irrigated areas of four counties in the province of Santiago del Estero, Argentina. The diagnosis was confirmed by serology, and there was no evidence of involvement of Western or Venezuelan equine encephalitis viruses. The overall incidence of equine encephalitis was estimated 17%, the case-fatality rate at 61% and the inapparent: apparent infection ratio less than or equal to 2.9:1. This is the first localized epizootic defined in Argentina and the first in which EEE has been found as the sole etiologic arbovirus. This posed the possibility to look for human infection in the area. In spite of a careful surveillance, no evidence of human disease or infection was found, differing from the situation in USA where EEE virus is a public health problem. Nevertheless vector/s and vertebrate hosts involved in the transmission cycle in Argentina remain unknown, precluding at present speculations on the potential human risk.
1981年，阿根廷圣地亚哥-德尔埃斯特罗省四个县的灌溉区发生了一起东部马脑炎（EEE）局部流行疫情。通过血清学确诊，没有证据表明西部或委内瑞拉马脑炎病毒参与其中。马脑炎的总体发病率估计为17%，病死率为61%，隐性感染与显性感染的比例小于或等于2.9:1。这是阿根廷定义的首例局部流行疫情，也是首次发现EEE为唯一病原虫媒病毒的疫情。这使得有可能在该地区寻找人类感染情况。尽管进行了仔细监测，但未发现人类疾病或感染的证据，这与美国的情况不同，在美国，EEE病毒是一个公共卫生问题。然而，阿根廷传播周期中涉及的媒介和脊椎动物宿主仍然未知，目前无法推测潜在的人类风险。
