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整合本科数学与生物学——以正在进行的生物医学研究为重点的跨学科教学。

Desegregating undergraduate mathematics and biology--interdisciplinary instruction with emphasis on ongoing biomedical research.

作者信息

Robeva Raina

机构信息

Department of Mathematical Sciences, Sweet Briar College, Sweet Briar, Virginia, USA.

出版信息

Methods Enzymol. 2009;454:305-21. doi: 10.1016/S0076-6879(08)03812-3.

Abstract

The remarkable advances in the field of biology in the last decade, specifically in the areas of biochemistry, genetics, genomics, proteomics, and systems biology, have demonstrated how critically important mathematical models and methods are in addressing questions of vital importance for these disciplines. There is little doubt that the need for utilizing and developing mathematical methods for biology research will only grow in the future. The rapidly increasing demand for scientists with appropriate interdisciplinary skills and knowledge, however, is not being reflected in the way undergraduate mathematics and biology courses are structured and taught in most colleges and universities nationwide. While a number of institutions have stepped forward and addressed this need by creating and offering interdisciplinary courses at the juncture of mathematics and biology, there are still many others at which there is little, if any, interdisciplinary interaction between the curricula. This chapter describes an interdisciplinary course and a textbook in mathematical biology developed collaboratively by faculty from Sweet Briar College and the University of Virginia School of Medicine. The course and textbook are designed to provide a bridge between the mathematical and biological sciences at the lower undergraduate level. The course is developed for and is being taught in a liberal arts setting at Sweet Briar College, Virginia, but some of the advanced modules are used in a course at the University of Virginia for advanced undergraduate and beginning graduate students. The individual modules are relatively independent and can be used as stand-alone projects in conventional mathematics and biology courses. Except for the introductory material, the course and textbook topics are based on current biomedical research.

摘要

过去十年间,生物学领域取得了显著进展,尤其是在生物化学、遗传学、基因组学、蛋白质组学和系统生物学等方面。这些进展表明,数学模型和方法对于解决这些学科中至关重要的问题具有何等关键的重要性。毫无疑问,未来对生物学研究中运用和发展数学方法的需求只会不断增长。然而,全国大多数高校本科数学和生物学课程的设置与教学方式,并未反映出对具备适当跨学科技能和知识的科学家的快速增长的需求。虽然一些机构已经站出来,通过在数学与生物学的交叉点开设跨学科课程来满足这一需求,但仍有许多其他机构,其课程之间几乎没有(即便有也极少)跨学科互动。本章介绍了由斯威特布莱尔学院和弗吉尼亚大学医学院的教师合作开发的一门数学生物学跨学科课程及一本教材。该课程和教材旨在为本科低年级学生搭建数学与生物科学之间的桥梁。这门课程是为弗吉尼亚州斯威特布莱尔学院的文科环境开发并授课的,但其中一些高级模块在弗吉尼亚大学的一门课程中供本科高年级学生和研究生一年级学生使用。各个模块相对独立,可以用作传统数学和生物学课程中的独立项目。除了入门材料外,该课程和教材的主题均基于当前的生物医学研究。

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