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用先前在小型猪肾(MPK)细胞系中适应的猪霍乱病毒(HCV)兔化中国株对猪进行免疫接种后的保护试验,以抵抗强毒HCV的感染攻击。

Protection tests in pigs vaccinated with the lapinized Chinese strain of hog cholera virus (HCV) previously adapted in a minipig kidney (MPK) cell line, to challenge infection with virulent HCV.

作者信息

Gualandi G L, Ferrari M, Cardeti G, Boldini M, Buonavoglia C

机构信息

Scuola per la Ricerca Scientifica, Fondazione Iniziative Zooprofilattiche e Zootecniche, Brescia, Italy.

出版信息

Microbiologica. 1991 Jul;14(3):213-7.

PMID:1921741
Abstract

Pigs which had been vaccinated with the Lapinized Chinese strain of Hog Cholera Virus previously adapted in a minipig cell line cultures (MPK-LC-HCV), resultet to be protected when they were subjected to challenge infection with virulent Hog Cholera Virus (HCV) 6 or 11 months later. The challenge virus was never isolated from any of the vaccinated pigs. The MPK-LC-HCV vaccine induced a significant rise of the antibody titer to the HCV in pigs kept under field conditions.

摘要

先前在小型猪细胞系培养物(MPK-LC-HCV)中适应的兔化中国猪瘟病毒株疫苗接种的猪,在6或11个月后受到强毒猪瘟病毒(HCV)攻击感染时,结果显示受到了保护。在任何接种疫苗的猪中都从未分离出攻击病毒。MPK-LC-HCV疫苗在田间条件下饲养的猪中诱导了针对HCV的抗体滴度显著升高。

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