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[癫痫持续状态的鉴别诊断]

[Differential diagnosis of status epilepticus].

作者信息

Navarro V, Fischer C, Convers P

机构信息

Unité d'épileptologie et département de neurophysiologie clinique, bâtiment Paul-Castaigne, hôpital de la Pitié-Salpêtrière, AP-HP, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.

出版信息

Rev Neurol (Paris). 2009 Apr;165(4):321-7. doi: 10.1016/j.neurol.2008.11.005. Epub 2009 Feb 13.

DOI:10.1016/j.neurol.2008.11.005
PMID:19217635
Abstract

The diagnosis of status epilepticus can be retained, wrongly, in several circumstances. Nonepileptic pseudoseizures from a psychiatric origin and some movement disorders can mimic convulsive status epilepticus. Encephalopathy of various causes (post-anoxic, metabolic, toxic, Creutzfeldt-Jakob disease) can be wrongly taken for non-convulsive status epilepticus, mainly due to inadequate interpretation of the electroencephalogram (EEG). In these encephalopathies, the existence of (non-epileptic) myoclonus and the abolition of the EEG abnormalities with the use of a benzodiazepine (without correction of the clinical symptoms) are additional confounding factors, leading to false diagnosis. Nevertheless, in general, the diagnosis of status epilepticus can be confirmed or rejected base on a combined analysis of the clinical data and the EEG.

摘要

在某些情况下,癫痫持续状态的诊断可能会被错误地保留。源于精神疾病的非癫痫性假性发作和一些运动障碍可模仿惊厥性癫痫持续状态。各种病因(缺氧后、代谢性、中毒性、克雅氏病)引起的脑病可能会被误诊为非惊厥性癫痫持续状态,主要原因是对脑电图(EEG)的解读不足。在这些脑病中,(非癫痫性)肌阵挛的存在以及使用苯二氮䓬类药物后脑电图异常消失(而临床症状未改善)是额外的混淆因素,可导致误诊。然而,总体而言,癫痫持续状态的诊断可以基于临床数据和脑电图的综合分析得到证实或排除。

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