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Human immunodeficiency virus infection in cells of myeloid-monocytic lineage.

作者信息

Ushijima H, Dairaku M, Honma H, Yamaguchi K, Shimizu H, Tsuchie H, Abe K, Yamamoto A, Hoshino H, Müller W E

机构信息

Division of AIDS Virus, National Institute of Health, Tokyo.

出版信息

Microbiol Immunol. 1991;35(6):487-92. doi: 10.1111/j.1348-0421.1991.tb01579.x.

Abstract

We established persistent infection with a strain of human immunodeficiency virus type 1, HTLV-IIIB, in a promyelomonocytic cell line, ML-1 (CD4 antigen nearly negative and CD4 mRNA negative), and a promonocytic cell line, THP-1 (CD4 antigen positive). Different reaction of giant cell formation was found after co-cultivation of infected and uninfected cells of ML-1, HL-60, THP-1 and U-937 cell lines with uninfected and infected MOLT4 (a T-lymphoma cell line).

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