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非引导性骶髂关节注射:对脊柱关节病患者顽固性臀部疼痛的影响。

Unguided sacroiliac injection: effect on refractory buttock pain in patients with spondyloarthropathies.

作者信息

Sadreddini Shahram, Noshad Hamid, Molaeefard Mahshid, Ardalan Mohammad-Reza, Ghojazadeh Morteza, Shakouri Seyed-Kazem

机构信息

Tabriz University (Medical Sciences), Tabriz, Iran.

出版信息

Presse Med. 2009 May;38(5):710-6. doi: 10.1016/j.lpm.2008.09.028. Epub 2009 Feb 13.

DOI:10.1016/j.lpm.2008.09.028
PMID:19217752
Abstract

OBJECTIVE

This study was designed to evaluate the efficacy and safety of unguided sacroiliac injections for refractory sacroiliac pain due to spondyloarthropathies.

METHOD

An open-label clinical trial lasted 20 weeks for each of 29 patients, with different subtypes of spondyloarthropathies. It was conducted from September 2004 through January 2007. In patients with refractory inflammatory buttock pain (the inclusion criterion), we performed unguided injections of triamcinolone acetonide 40 mg into each sacroiliac joint on an outpatient basis. Assessments by patients and clinicians were recorded at baseline and every 4 weeks until the end of the study.

RESULTS

At week 4, significant decreases were seen in the patients' assessment of pain, morning stiffness, and sleep disturbance and in the clinicians' sacroiliac examination score. Pain reduction, as scored by patient and clinician, was maintained through week 20. No significant improvement was seen on the finger-to-floor or Schober tests. Magnetic resonance imaging (MRI) results showed a significant decrease in inflammatory scores after the sacroiliac injections. The patients' pain score and sleep disturbance were both clearly associated with the MRI inflammation index. The injection was well tolerated by all patients and no serious adverse event was seen.

CONCLUSION

This technique for sacroiliac injection was effective, and the final results showed a significant improvement in pain, similar to that with imaging-guided interventions. Trained physicians can perform this procedure safely in outpatient settings.

摘要

目的

本研究旨在评估非引导性骶髂关节注射治疗脊柱关节病所致难治性骶髂关节疼痛的疗效和安全性。

方法

一项开放标签的临床试验,对29例患有不同亚型脊柱关节病的患者,每人持续20周。该试验于2004年9月至2007年1月进行。对于难治性炎性臀部疼痛患者(纳入标准),我们在门诊对每个骶髂关节进行非引导性注射40mg曲安奈德。在基线时以及研究结束前每4周记录患者和临床医生的评估结果。

结果

在第4周时,患者对疼痛、晨僵和睡眠障碍的评估以及临床医生的骶髂关节检查评分均显著下降。患者和临床医生评分的疼痛减轻在第20周时仍得以维持。在手指触地试验或Schober试验中未见明显改善。磁共振成像(MRI)结果显示骶髂关节注射后炎症评分显著降低。患者的疼痛评分和睡眠障碍均与MRI炎症指数明显相关。所有患者对注射耐受性良好,未观察到严重不良事件。

结论

这种骶髂关节注射技术是有效的,最终结果显示疼痛有显著改善,类似于影像引导干预的效果。经过培训的医生可以在门诊环境中安全地进行此操作。

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