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患有暴饮暴食症的肥胖患者的代谢综合征及其行为关联

The metabolic syndrome and behavioral correlates in obese patients with binge eating disorder.

作者信息

Roehrig Megan, Masheb Robin M, White Marney A, Grilo Carlos M

机构信息

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.

出版信息

Obesity (Silver Spring). 2009 Mar;17(3):481-6. doi: 10.1038/oby.2008.560. Epub 2008 Dec 11.

Abstract

This study examined the frequency of the metabolic syndrome (MetSyn) and explored behavioral eating- and weight-related correlates in obese patients with binge eating disorder (BED). Ninety-three treatment-seeking obese BED patients (22 men and 71 women) with and without the MetSyn were compared on demographic features and a number of current and historical eating and weight variables. Sixty percent of the obese patients with BED met criteria for the MetSyn, with men and whites having significantly higher rates than women and African Americans, respectively. Patients with vs. without coexisting MetSyn did not differ significantly in self-reported frequency of binge eating or severity of eating disorder psychopathology. Multivariate hierarchical logistic regression analysis revealed that, after controlling for gender, ethnicity, and BMI, fewer episodes of weight cycling and regular meal skipping were significant predictors of the MetSyn. These findings suggest that lifestyle behaviors including weight loss attempts and regular meal consumption may be potential targets for prevention and/or treatment of the MetSyn in obese patients with BED.

摘要

本研究调查了代谢综合征(MetSyn)的发生率,并探讨了患有暴饮暴食症(BED)的肥胖患者与饮食及体重相关的行为关联因素。对93名寻求治疗的肥胖BED患者(22名男性和71名女性)进行了比较,这些患者伴有或不伴有MetSyn,比较内容包括人口统计学特征以及一些当前和既往的饮食及体重变量。60%的肥胖BED患者符合MetSyn标准,男性和白人的发生率分别显著高于女性和非裔美国人。伴有与不伴有共存MetSyn的患者在自我报告的暴饮暴食频率或饮食失调精神病理学严重程度方面无显著差异。多变量分层逻辑回归分析显示,在控制了性别、种族和体重指数(BMI)后,较少的体重波动发作次数和经常不规律进餐是MetSyn的显著预测因素。这些发现表明,包括减肥尝试和规律进餐在内的生活方式行为可能是预防和/或治疗肥胖BED患者MetSyn的潜在靶点。

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