Uldry P A, Despland P A, Regli F
Centre EEG-EMG et de diagnostic neurophysiologique, service de neurologie, centre hospitalier universitaire vaudois (CHUV), Lausanne, Suisse.
Neurophysiol Clin. 1991 May;21(2):85-94. doi: 10.1016/s0987-7053(05)80063-2.
Alpha coma is a relatively rare variety of EEG resulting from diffuse cerebral anoxia, focal brainstem lesions, metabolic disturbances or intoxications. It is a monotonous, unreactive and anteriorly predominant activity of less than 50 microV and of 8 to 13 Hz. Twenty cases of alpha coma are reported: 16 resulting from anoxic encephalopathy, 2 from brain stem strokes, and 2 from metabolic encephalopathy. Cardiac arrest was the main cause of alpha coma (10 cases); a large number of patients (7 cases) died, or have survived with severe neurologic deficits (2 cases). In 2 cases there was a metabolic-toxic cause (benzodiazepines and parathion intoxication). The 2 patients with pontomesencephalic haemorrhage died. The physiopathogenicity of alpha coma, which remains obscure, is also discussed.
α昏迷是一种相对罕见的脑电图表现，由弥漫性脑缺氧、局灶性脑干病变、代谢紊乱或中毒引起。它是一种单调、无反应且以额部为主的活动，波幅小于50微伏，频率为8至13赫兹。报告了20例α昏迷病例：16例由缺氧性脑病引起，2例由脑干中风引起，2例由代谢性脑病引起。心脏骤停是α昏迷的主要原因（10例）；大量患者（7例）死亡，或存活但伴有严重神经功能缺损（2例）。2例有代谢 - 中毒原因（苯二氮䓬类药物和对硫磷中毒）。2例脑桥中脑出血患者死亡。文中还讨论了α昏迷仍不明确的生理致病性。
