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[α波昏迷:20例回顾性报告]

[Alpha coma: rectrospective presentation of 20 cases].

作者信息

Uldry P A, Despland P A, Regli F

机构信息

Centre EEG-EMG et de diagnostic neurophysiologique, service de neurologie, centre hospitalier universitaire vaudois (CHUV), Lausanne, Suisse.

出版信息

Neurophysiol Clin. 1991 May;21(2):85-94. doi: 10.1016/s0987-7053(05)80063-2.

Abstract

Alpha coma is a relatively rare variety of EEG resulting from diffuse cerebral anoxia, focal brainstem lesions, metabolic disturbances or intoxications. It is a monotonous, unreactive and anteriorly predominant activity of less than 50 microV and of 8 to 13 Hz. Twenty cases of alpha coma are reported: 16 resulting from anoxic encephalopathy, 2 from brain stem strokes, and 2 from metabolic encephalopathy. Cardiac arrest was the main cause of alpha coma (10 cases); a large number of patients (7 cases) died, or have survived with severe neurologic deficits (2 cases). In 2 cases there was a metabolic-toxic cause (benzodiazepines and parathion intoxication). The 2 patients with pontomesencephalic haemorrhage died. The physiopathogenicity of alpha coma, which remains obscure, is also discussed.

摘要

α昏迷是一种相对罕见的脑电图表现,由弥漫性脑缺氧、局灶性脑干病变、代谢紊乱或中毒引起。它是一种单调、无反应且以额部为主的活动,波幅小于50微伏,频率为8至13赫兹。报告了20例α昏迷病例:16例由缺氧性脑病引起,2例由脑干中风引起,2例由代谢性脑病引起。心脏骤停是α昏迷的主要原因(10例);大量患者(7例)死亡,或存活但伴有严重神经功能缺损(2例)。2例有代谢 - 中毒原因(苯二氮䓬类药物和对硫磷中毒)。2例脑桥中脑出血患者死亡。文中还讨论了α昏迷仍不明确的生理致病性。

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