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来自极热光纤尖端的热传导有助于静脉曲张的静脉内激光消融。

Heat conduction from the exceedingly hot fiber tip contributes to the endovenous laser ablation of varicose veins.

作者信息

van den Bos Renate R, Kockaert Michael A, Martino Neumann H A, Bremmer Rolf H, Nijsten Tamar, van Gemert Martin J C

机构信息

Department of Dermatology, Erasmus Medical Centre, P.O. BOX 2040, 3000 CA, Rotterdam, The Netherlands.

出版信息

Lasers Med Sci. 2009 Mar;24(2):247-51. doi: 10.1007/s10103-008-0639-y. Epub 2009 Feb 14.

DOI:10.1007/s10103-008-0639-y
PMID:19219485
Abstract

Lower-extremity venous insufficiency is a common condition, associated with considerable health care costs. Endovenous laser ablation is increasingly used as therapy, but its mechanism of action is insufficiently understood. Here, direct absorption of the laser light, collapsing steam bubbles and direct fiber-wall contact have all been mentioned as contributing mechanisms. Because fiber tips have reported temperatures of 800-1,300 degrees C during endovenous laser ablation, we sought to assess whether heat conduction from the hot tip could cause irreversible thermal injury to the venous wall. We approximated the hot fiber tip as a sphere with diameter equal to the fiber diameter, having a steady state temperature of 800 degrees C or 1,000 degrees C. We computed venous wall temperatures due to heat conduction from this hot sphere, varying the pullback velocity of the fiber and the diameter of the vein. Venous wall temperatures corresponding to irreversible injury resulted for a 3 mm diameter vein and pullback velocities <3 mm/s but not for 5 mm and > or =1 mm/s. The highest wall temperature corresponded to the position on the wall closest to the fiber tip, hence it moves longitudinally in parallel with the moving fiber tip. We concluded that heat conduction from the hot fiber tip is a contributing mechanism in endovenous laser ablation.

摘要

下肢静脉功能不全是一种常见病症,会产生相当高的医疗费用。静脉腔内激光消融术越来越多地被用作治疗方法,但其作用机制尚未得到充分了解。在此,激光的直接吸收、蒸汽泡的塌陷以及光纤与血管壁的直接接触都被提及为可能的作用机制。由于在静脉腔内激光消融过程中,光纤尖端的温度据报道可达800 - 1300摄氏度,我们试图评估来自热尖端的热传导是否会对静脉壁造成不可逆的热损伤。我们将热光纤尖端近似为一个直径等于光纤直径的球体,其稳态温度为800摄氏度或1000摄氏度。我们计算了由于该热球体的热传导导致的静脉壁温度,改变了光纤的回撤速度和静脉直径。对于直径为3毫米的静脉,当回撤速度<3毫米/秒时,会出现对应不可逆损伤的静脉壁温度,但对于5毫米以及≥1毫米/秒的情况则不会。最高壁温对应于静脉壁上最靠近光纤尖端的位置,因此它与移动的光纤尖端平行纵向移动。我们得出结论,热光纤尖端的热传导是静脉腔内激光消融术中的一个作用机制。

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本文引用的文献

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Optical Properties of Circulating Human Blood in the Wavelength Range 400-2500 nm.400 - 2500纳米波长范围内循环人体血液的光学特性
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Endovenous laser ablation-induced complications: review of the literature and new cases.腔内激光消融术引起的并发症:文献综述及新病例报告
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Endovenous laser ablation: mechanism of action.静脉腔内激光消融:作用机制
光声引导下的静脉内激光消融:特性与犬类研究。
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Photoacoustic Imaging for Image-guided Endovenous Laser Ablation Procedures.光声成象在影像引导静脉内激光烧蚀程序中的应用。
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Foaming of blood in endovenous laser treatment.静脉内激光治疗中的血液发泡现象。
Lasers Med Sci. 2018 Nov;33(8):1821-1826. doi: 10.1007/s10103-018-2552-3. Epub 2018 May 28.
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Ins and outs of endovenous laser ablation: afterthoughts.静脉内激光消融的来龙去脉:反思
Lasers Med Sci. 2014 Mar;29(2):513-8. doi: 10.1007/s10103-013-1499-7. Epub 2014 Jan 8.
8
How we started performing endovenous thermal ablation procedures: a personal history.我们如何开始进行静脉内热消融手术:个人经历。
Lasers Med Sci. 2014 Mar;29(2):383-5. doi: 10.1007/s10103-013-1462-7. Epub 2014 Jan 5.
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Endovenous laser ablation (EVLA): a review of mechanisms, modeling outcomes, and issues for debate.静脉腔内激光消融术(EVLA):作用机制、模拟结果及争议问题综述
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10
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