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静脉内激光治疗中的血液发泡现象。

Foaming of blood in endovenous laser treatment.

作者信息

Chudnovskii Vladimir, Mayor Aleksandr, Kiselev Artem, Yusupov Vladimir

机构信息

V.I. Il'ichev Pacific Oceanological Institute Far Eastern Branch Russian academy of sciences (POI FEB RAS), 43 Baltiyskaya st., Vladivostok, Russia, 690041.

Institute of Automation and Control Processes Far Eastern Branch of the Russian Academy of Sciences (IACP FEB RAS), Radio st., Vladivostok, Russia, 690041.

出版信息

Lasers Med Sci. 2018 Nov;33(8):1821-1826. doi: 10.1007/s10103-018-2552-3. Epub 2018 May 28.

Abstract

This work is dedicated to a challenging issue of modern phlebology-establishment of a physical mechanism of the endovenous laser treatment (EVLT) against great saphenous vein incompetence (protuberant varicosities). Using optical and acoustical methods, we have studied the laser-induced formation of microbubbles in an aqueous solution of surface-active substances, serum, and blood directly in patients while conducting EVLT of the great saphenous vein in a clinical setting. We have used lasers with wavelengths 0.97 and 1.47 μm. Their radiation was transmitted through a quartz-quartz polymer fiber 600 μm in diameter. It has been found that in all cases, the laser beam with moderate power (1-10 W) supplied through an optical fiber leads to the formation of micro-bubbled foam. It has been shown that laser exposure during EVLT induces blood boiling, which results in heating of the venous walls (thermal destruction of the intima) and provides effective foam occlusion of the blood vessels (hemostasis). Necessary and sufficient conditions for a successful EVLT are associated with the thermal destruction of intima and laser-induced foam hemostasis.

摘要

这项工作致力于解决现代静脉学中一个具有挑战性的问题——建立针对大隐静脉功能不全(突出静脉曲张)的静脉内激光治疗(EVLT)的物理机制。我们使用光学和声学方法,在临床环境中对大隐静脉进行EVLT时,直接在患者体内研究了表面活性物质、血清和血液的水溶液中激光诱导的微泡形成。我们使用了波长为0.97和1.47μm的激光。它们的辐射通过直径为600μm的石英 - 石英聚合物光纤传输。已发现,在所有情况下,通过光纤提供的中等功率(1 - 10W)激光束会导致微泡泡沫的形成。研究表明,EVLT期间的激光照射会引起血液沸腾,进而导致静脉壁受热(内膜热破坏),并实现血管的有效泡沫闭塞(止血)。成功进行EVLT的必要和充分条件与内膜的热破坏和激光诱导的泡沫止血有关。

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