Van der Wal B C H, Rahmy A I A, Grimm B, Blake G M, Heyligers I C, Tonino A J
Department of Orthopaedics, Atrium Medical Centre, Heerlen, The Netherlands.
Hip Int. 2006 Jan-Mar;16(1):8-17.
Proximal bone resorption and an increased fracture rate in the ABG-I stem has been shown. For these reasons the ABG-I stem design was changed to the ABG-II. In this study periprosthetic bone loss around the ABG-I vs ABG-II is compared to verify if the design changes resulted in improved proximal bone preservation.
51 patients were randomised to either the ABG-I or ABG-II hip prosthesis. Periprosthetic BMD change at various time points was measured using DEXA. Between the two groups (age, gender, weight etc.) no statistical difference was encountered. Compared to the baseline at two years the ABG-II preserved bone better proximally (e.g. zone 7: ABG-II: -3.7%, ABG-I: -11.9%, p=0.05) than the ABG-I. Distally, the trend was opposite and less bone loss was measured for the ABG-I than the ABG-II in zones 3, 4 and 5 (n.s.).
this study confirms the philosophy behind the design changes from the ABG-I to ABG-II stem where increased elasticity, more proximal HA-coating, a shorter and distally polished stem, were meant to reduce proximal bone resorption. In future this may lead to fewer periprosthetic fractures and to less complicated revision surgery.
已证实ABG - I型柄存在近端骨吸收且骨折率增加。基于这些原因,ABG - I型柄的设计变更为ABG - II型。在本研究中,对ABG - I型与ABG - II型周围的假体周围骨丢失情况进行比较,以验证设计变更是否能改善近端骨保留情况。
51例患者被随机分为接受ABG - I型或ABG - II型髋关节假体。使用双能X线吸收法(DEXA)测量不同时间点的假体周围骨密度变化。两组之间(年龄、性别、体重等)未发现统计学差异。与两年时的基线相比,ABG - II型在近端(如7区:ABG - II型:-3.7%,ABG - I型:-11.9%,p = 0.05)比ABG - I型能更好地保留骨。在远端,趋势相反,ABG - I型在3区、4区和5区的骨丢失量比ABG - II型少(无统计学意义)。
本研究证实了从ABG - I型柄到ABG - II型柄设计变更背后的理念,即增加弹性、更多近端羟基磷灰石涂层、更短且远端抛光的柄,旨在减少近端骨吸收。未来这可能会导致更少的假体周围骨折和更简单的翻修手术。