Zhong Jiang-Chun, Hou Shi-Cong, Bian Qing-Hua, Yin Min-Min, Na Ri-Song, Zheng Bing, Li Zhi-Yuan, Liu Shang-Zhong, Wang Min
Department of Applied Chemistry, China Agricultural University, Beijing, China.
Chemistry. 2009;15(13):3069-71. doi: 10.1002/chem.200900070.
Meeting the challenge: The zinc/amino alcohol catalyzed enantioselective addition of terminal alkynes to aldehydes is effective with both phenylacetylene and methyl propiolate, leading to chiral secondary propargyl alcohols with very high enantioselectivity (see scheme).
锌/氨基醇催化的末端炔烃对醛的对映选择性加成反应，对于苯乙炔和丙酸甲酯均有效，能以非常高的对映选择性生成手性仲炔丙醇（见反应式）。
