霍乱毒素需要氧化型烟酰胺腺嘌呤二核苷酸来激活纯化的大鼠肝细胞膜中的腺苷酸环化酶。
Cholera toxin requires oxidized nicotinamide-adenine dinucleotide to activate adenylate cyclase in purified rat liver plasma membranes.
作者信息
Martin B R, Houslay M D, Kennedy E L
出版信息
Biochem J. 1977 Mar 1;161(3):639-42. doi: 10.1042/bj1610639.
Abstract
Activation of adenylate cyclase in isolated rat liver plasma membranes by cholera toxin was demonstrated. The activation requires the presence of NAD+ and ATP and is irreversible.
摘要
已证实在离体大鼠肝细胞膜中霍乱毒素可激活腺苷酸环化酶。该激活作用需要烟酰胺腺嘌呤二核苷酸（NAD+）和三磷酸腺苷（ATP）的存在，并且是不可逆的。
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