霍乱毒素需要氧化型烟酰胺腺嘌呤二核苷酸来激活纯化的大鼠肝细胞膜中的腺苷酸环化酶。
Cholera toxin requires oxidized nicotinamide-adenine dinucleotide to activate adenylate cyclase in purified rat liver plasma membranes.
作者信息
Martin B R, Houslay M D, Kennedy E L
出版信息
Biochem J. 1977 Mar 1;161(3):639-42. doi: 10.1042/bj1610639.
Abstract
Activation of adenylate cyclase in isolated rat liver plasma membranes by cholera toxin was demonstrated. The activation requires the presence of NAD+ and ATP and is irreversible.
摘要
已证实在离体大鼠肝细胞膜中霍乱毒素可激活腺苷酸环化酶。该激活作用需要烟酰胺腺嘌呤二核苷酸（NAD+）和三磷酸腺苷（ATP）的存在，并且是不可逆的。
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本文引用的文献
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A highly sensitive adenylate cyclase assay.一种高灵敏度的腺苷酸环化酶检测方法。
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Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats.胰高血糖素对糖尿病大鼠肝脏中环磷酸腺苷及碳水化合物代谢的影响。
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Mechanism of activation of adenylate cyclase by cholera toxin.霍乱毒素激活腺苷酸环化酶的机制。
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