Morelli Umberto, Cirocchi Roberto, Mecarelli Valerio, Farinella Eriberto, La Mura Francesco, Ronca Paolo, Giustozzi Gianmario, Sciannameo Francesco
Università degli Studi di Perugia, Clinica Chirurgica Generale e d'Urgenza, Azienda Ospedaliera S, Maria, Terni, Italy.
J Med Case Rep. 2009 Feb 16;3:65. doi: 10.1186/1752-1947-3-65.
Skin metastasis from internal carcinoma rarely occurs. It has an incidence of 0.7 to 9% and it may be the first sign of an unknown malignancy. However, it can also occur during follow-up.
A 90-year-old female patient was admitted to our surgical division with a diagnosis of anemia from a bleeding gastric adenocarcinoma. She underwent a gastric resection and Billroth II retrocolic Hofmeister/Finsterer reconstruction. She developed an enteric fistula, which needed a permanent abdominal drain until the 60th postoperative day. After 12 months she was readmitted to our division with subacute small bowel obstruction and an erythematous swelling on the right side of the abdomen. Biopsies characterized it as a cutaneous metastasis from the gastric adenocarcinoma. No surgical therapy was performed given her poor clinical condition.
Skin metastasis from carcinomas of the upper gastrointestinal tract is very rare. Persisting erythematous nodules must be biopsied in order to diagnose cutaneous metastases and to recognize them early and start prompt therapy with anti-tumour agents before the occurrence of massive visceral metastases.
源自体内癌的皮肤转移很少见。其发生率为0.7%至9%,可能是未知恶性肿瘤的首发症状。然而,它也可能在随访期间出现。
一名90岁女性患者因胃腺癌出血导致贫血而入住我院外科。她接受了胃切除术及毕罗Ⅱ式结肠后霍夫迈斯特/芬斯特勒重建术。她出现了肠瘘,在术后第60天之前需要长期留置腹腔引流管。12个月后,她因亚急性小肠梗阻和腹部右侧红斑性肿胀再次入住我科。活检显示为胃腺癌皮肤转移。鉴于其临床状况较差,未进行手术治疗。
上消化道癌的皮肤转移非常罕见。对于持续存在的红斑性结节必须进行活检,以便诊断皮肤转移,尽早识别并在发生大量内脏转移之前开始使用抗肿瘤药物进行及时治疗。