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意大利银屑病患者高血压、糖尿病和肥胖的风险因素:一项关于社会人口学特征、吸烟习惯和饮酒情况的调查

Risk factors of hypertension, diabetes and obesity in Italian psoriasis patients: a survey on socio-demographic characteristics, smoking habits and alcohol consumption.

作者信息

Altobelli Emma, Petrocelli Reimondo, Maccarone Mara, Altomare Gianfranco, Argenziano Giuseppe, Giannetti Alberto, Peserico Andrea, Vena Gino A, Tiberti Sergio, Chimenti Sergio, Peris Ketty

机构信息

Department of Internal Medicine and Public Health, University of L'Aquila, Coppito-Delta 6, 67100 L'Aquila, Italy.

出版信息

Eur J Dermatol. 2009 May-Jun;19(3):252-6. doi: 10.1684/ejd.2009.0644. Epub 2009 Feb 17.

Abstract

We evaluated risk factors such as socio-demographic characteristics, smoking habits and alcohol consumption, associated with hypertension, diabetes and obesity in psoriasis patients, in order to plan health education programs that could prevent the onset or progression of co-morbidities. The study population consisted of 1376 patients with psoriasis who were consecutively recruited at 21 Italian Departments of Dermatology. Information concerning socio-demographic variables, smoking and alcohol consumption, and the presence of chronic disorders such as hypertension, type 2 diabetes and obesity was collected. The risk of co-morbidities according to the various exposure variables was calculated using logistic regression models. Psoriasis patients living in extremely urban areas showed the highest risk of diabetes (OR = 1.99, 95% CI 1.06-5.23) and obesity (OR = 2.60, 95% CI 1.10-16.12), as compared to patients living in rural areas. The OR for hypertension was higher for smokers (> 15 cigarettes per day, OR = 1.37, 95% CI 1.01-2.03) and drinkers (> 2 glasses/day of wine, OR = 2.11, 95% CI 1.31-3.40). The OR for diabetes or obesity was higher for drinkers: 1 drink/day (OR = 1.93, 95% CI 1.01-3.67) and > 1 drink/day of spirits (OR = 2.90, 95% CI 1.43-5.82), respectively. The results of our survey highlight the need to detect psoriasis patients with different susceptibilities to co-morbidities in order to plan specific health campaigns aimed at changing people's lifestyles with respect to smoking, drinking and diet.

摘要

我们评估了社会人口统计学特征、吸烟习惯和饮酒等与银屑病患者高血压、糖尿病和肥胖相关的风险因素,以便制定能够预防合并症发生或进展的健康教育计划。研究人群包括在意大利21个皮肤科连续招募的1376例银屑病患者。收集了有关社会人口统计学变量、吸烟和饮酒情况以及高血压、2型糖尿病和肥胖等慢性疾病存在情况的信息。使用逻辑回归模型计算了根据各种暴露变量的合并症风险。与生活在农村地区的患者相比,生活在极端城市地区的银屑病患者患糖尿病(OR = 1.99,95% CI 1.06 - 5.23)和肥胖(OR = 2.60,95% CI 1.10 - 16.12)的风险最高。吸烟者(每天>15支香烟,OR = 1.37,95% CI 1.01 - 2.03)和饮酒者(每天>2杯葡萄酒,OR = 2.11,95% CI 1.31 - 3.40)患高血压的OR更高。饮酒者患糖尿病或肥胖的OR更高:每天1杯(OR = 1.93,95% CI 1.01 - 3.67)和每天>1杯烈酒(OR = 2.90,95% CI 1.43 - 5.82)。我们的调查结果强调,有必要识别对合并症有不同易感性的银屑病患者,以便制定旨在改变人们在吸烟、饮酒和饮食方面生活方式的特定健康宣传活动。

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