参与病毒介导的膜变化的表面成分。
Surface components involved in virally mediated membrane changes.
作者信息
Micklem K J, Pasternak C A
出版信息
Biochem J. 1977 Feb 15;162(2):405-10. doi: 10.1042/bj1620405.
Abstract
- Virally mediated permeability changes are not brought about by neuraminidase or other enzyme. They are not mimicked by local anaesthetics such as benzyl alcohol or dibucaine. 2. Virus induces an increase in the exchange rate of membrane-bound Ca2+. The temperature-dependence, and sensitivity to concanavalin A, of the permeability change and of Ca2+ exchange are similar. 3. It is concluded that an increase in the exchangeability of membrane-bound Ca2+ constitutes an early and specific event after the attachment of Sendai virus to cultured cells.
摘要
- 病毒介导的通透性变化不是由神经氨酸酶或其他酶引起的。它们也不会被局部麻醉剂如苄醇或丁卡因模拟。2. 病毒会导致膜结合Ca2+的交换速率增加。通透性变化和Ca2+交换的温度依赖性以及对刀豆球蛋白A的敏感性是相似的。3. 得出的结论是，膜结合Ca2+的交换能力增加是仙台病毒附着于培养细胞后的早期特异性事件。
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