Chen Ming, Wang Jing, Xie Mingxing, Wang Xinfang, Lv Qing, Wang Lei, Li Yan, Fu Manli
Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Provincial Key Laboratory of Molecular Imaging, Wuhan, China.
J Huazhong Univ Sci Technolog Med Sci. 2009 Feb;29(1):122-6. doi: 10.1007/s11596-009-0126-0. Epub 2009 Feb 18.
Left ventricular remodeling index (LVRI) was assessed in patients with hypertensive heart disease (HHD) and coronary artery disease (CAD) by real-time three-dimensional echocardiography (RT3DE). RT3DE data of 18 patients with HHD, 20 patients with CAD and 22 normal controls (NC) were acquired. Left ventricular end-diastolic volume (EDV) and left ventricular end-diastolic epicardial volume (EDVepi ) were detected by RT3DE and two-dimensional echocardiography Simpson biplane method (2DE). LVRI (left ventricular mass /EDV) was calculated and compared. The results showed that LVRI measurements detected by RT3DE and 2DE showed significant differences inter-groups (P<0.01). There was no significant difference in NC group (P>0.05), but significant difference in HHD and CAD intra-group (P<0.05). There was good positive correlations between LVRI detected by RT3DE and 2DE in NC and HHD groups (r=0.69, P<0.01; r=0.68, P<0.01), but no significant correlation in CAD group (r=0.30, P>0.05). It was concluded that LVRI derived from RT3DE as a new index for evaluating left ventricular remodeling can provide more superiority to LVRI derived from 2DE.
采用实时三维超声心动图（RT3DE）评估高血压性心脏病（HHD）和冠状动脉疾病（CAD）患者的左心室重构指数（LVRI）。获取了18例HHD患者、20例CAD患者和22例正常对照者（NC）的RT3DE数据。通过RT3DE和二维超声心动图辛普森双平面法（2DE）检测左心室舒张末期容积（EDV）和左心室舒张末期心外膜容积（EDVepi）。计算并比较LVRI（左心室质量/EDV）。结果显示，RT3DE和2DE检测的LVRI测量值在组间存在显著差异（P<0.01）。NC组无显著差异（P>0.05），但HHD组和CAD组内有显著差异（P<0.05）。NC组和HHD组中，RT3DE和2DE检测的LVRI之间存在良好的正相关（r=0.69，P<0.01；r=0.68，P<0.01），但CAD组无显著相关性（r=0.30，P>0.05）。结论是，RT3DE得出的LVRI作为评估左心室重构的新指标，相对于2DE得出的LVRI具有更多优势。
