Baumgaertel Anja, Weber Christine, Knop Katrin, Crecelius Anna, Schubert Ulrich S
Laboratory of Organic and Macromolecular Chemistry, Friedrich-Schiller-University Jena, Humboldtstr. 10, 07743 Jena, Germany.
Rapid Commun Mass Spectrom. 2009 Mar;23(6):756-62. doi: 10.1002/rcm.3933.
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) coupled with CID (collision-induced dissociation) has been used for the detailed characterization of two poly(2-ethyl-2-oxazoline)s as part of a continuing study of synthetic polymers by MALDI-TOF MS/MS. These experiments provided information about the variety of fragmentation pathways for poly(oxazoline)s. It was possible to show that, in addition to the eliminations of small molecules, like ethene and hydrogen, the McLafferty rearrangement is also a possible fragmentation route. A library of fragmentation pathways for synthetic polymers was also constructed and such a library should enable the fast and automated data analysis of polymers in the future.
作为通过基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF MS）对合成聚合物进行持续研究的一部分，将MALDI-TOF MS与碰撞诱导解离（CID）相结合，用于详细表征两种聚（2-乙基-2-恶唑啉）。这些实验提供了有关聚恶唑啉各种碎裂途径的信息。结果表明，除了消除乙烯和氢气等小分子外，麦克拉弗蒂重排也是一种可能的碎裂途径。还构建了合成聚合物的碎裂途径库，这样的库有望在未来实现聚合物的快速自动化数据分析。
