Yong M, Tolner B, Nagl S, Pedley R B, Chester K, Green A J, Mayer A, Sharma S, Begent R
UCL Cancer Institute, University College London, UK.
Protein Eng Des Sel. 2009 Mar;22(3):221-4. doi: 10.1093/protein/gzp003.
Research groups developing antibody therapies generate diverse data sets; the value of these sets would be compounded when shared or amalgamated. A complete amalgamation of diverse data sets requires data standards for information collection during experiments. We propose to define elements of the data standards in the form of common data elements (CDEs) in order to clarify each experiment's targets and data values. We have created a set of core information elements which we suggest should be collected from antibody therapy experiments. We propose these as a basis for community consultation with a view to defining a set of data standards which can be developed under the auspices of the Antibody Society.
致力于开发抗体疗法的研究团队会生成各种各样的数据集；若这些数据集能够共享或整合，其价值将得到提升。要全面整合不同的数据集，就需要在实验过程中制定信息收集的数据标准。我们建议以通用数据元素（CDE）的形式来定义数据标准的要素，以便明确每项实验的目标和数据值。我们已经创建了一组核心信息元素，建议从抗体疗法实验中收集这些元素。我们提议将这些元素作为社区协商的基础，以期定义一套可在抗体协会支持下制定的数据标准。
