Melamed Roman, Sprenkle Mark D, Ulstad Valerie K, Herzog Charles A, Leatherman James W
Division of Pulmonary-Critical Care, Hennepin County Medical Center, Minneapolis, MN.
Cardiology, Hennepin County Medical Center, Minneapolis, MN.
Chest. 2009 Jun;135(6):1416-1420. doi: 10.1378/chest.08-2440. Epub 2009 Feb 18.
Bedside transthoracic echocardiography (TTE) provides rapid and noninvasive hemodynamic assessment of critically ill patients but is limited by the immediate availability of experienced sonographers and cardiologists.
Forty-four patients in the medical ICU underwent near-simultaneous limited TTE performed by intensivists with minimal training in echocardiography, and a formal TTE that was performed by certified sonographers and was interpreted by experienced echocardiographers. Intensivists, blinded to the patient's diagnosis and the results of the formal TTE, were asked to determine whether left ventricular (LV) function was grossly normal or abnormal and to place LV function into one of the following three categories: 1, normal; 2, mildly to moderately decreased; and 3, severely decreased.
Using the formal TTE as the "gold standard," intensivists correctly identified normal LV function in 22 of 24 cases (92%) and abnormal LV function in 16 of 20 cases (80%). The kappa statistic for the agreement between intensivist and echocardiographer for any abnormality in LV function was 0.72 (95% confidence interval [CI], 0.52 to 0.93; p < 0.001). Intensivists correctly placed LV function into one of three categories in 36 of 44 cases (82%); in 6 of the 8 cases that were misclassified, the error involved an overestimation of LV function. The kappa statistic for agreement between the intensivist and echocardiographer with regard to placement into one of three categories of LV function was 0.68 (95% CI, 0.48 to 0.88; p < 0.001).
Intensivists were able to estimate LV function with reasonable accuracy using a hand-held unit in the ICU, despite having undergone minimal training in image acquisition and interpretation.
床旁经胸超声心动图(TTE)可为重症患者提供快速且无创的血流动力学评估,但受经验丰富的超声检查医师和心脏病专家能否即时到位的限制。
44例医学重症监护病房(ICU)患者接受了由接受过最少超声心动图培训的重症监护医师进行的近乎同步的有限TTE检查,以及由经认证的超声检查医师进行并由经验丰富的超声心动图专家解读的正式TTE检查。重症监护医师在对患者诊断及正式TTE结果不知情的情况下,被要求判断左心室(LV)功能是大致正常还是异常,并将LV功能分为以下三类之一:1,正常;2,轻度至中度降低;3,严重降低。
以正式TTE作为“金标准”,重症监护医师在24例中的22例(92%)中正确识别出正常LV功能,在20例中的16例(80%)中正确识别出异常LV功能。重症监护医师与超声心动图专家对LV功能任何异常的一致性kappa统计值为0.72(95%置信区间[CI],0.52至0.93;p<0.001)。重症监护医师在44例中的36例(82%)中正确地将LV功能归入三类之一;在8例分类错误的病例中,有6例错误是对LV功能的高估。重症监护医师与超声心动图专家在将LV功能归入三类之一方面的一致性kappa统计值为0.68(95%CI,0.48至0.88;p<0.001)。
尽管重症监护医师在图像采集和解读方面接受的培训很少,但他们能够在ICU中使用手持设备以合理的准确性估计LV功能。