Szirmai I G, Boldizsár F, Kerényi L
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1977 Jun;8(2):89-95.
Blood-gas (pO2, pCO2) and pH-changes of venous (v.jugularis interna) and arterial (A.femoralis) blood samples, furthermore glucose utilization and lactate-, pyruvate-production of brain were investigated during electroconvulsive treatment in relaxation of 45 psychotic patients. The blood-gas values and substrate concentrations were statistically evaluated and represented in a function of the characteristic phases of the postconvulsive EEG-activity. A correlation was found between the glucose metabolism of the brain and the postconvulsive recovery of EEG. The restitution of postconvulsive brain metabolism runs discontinuously in the first 12 minutes of postconvulsive state. In the phase of electric silence and periodic delta-waves the brain metabolism was shifted to anaerobic direction. During the treatment no anoxic anoxia or acidosis takes place during the seizure activity and restitution, the measurable metabolic changes are moderate and supposedly play no important role in the "effect" of treatment.
在45例精神病患者放松状态下进行电惊厥治疗期间,研究了颈内静脉血和股动脉血样本的血气(pO₂、pCO₂)及pH变化,此外还研究了脑的葡萄糖利用以及乳酸和丙酮酸生成情况。对血气值和底物浓度进行了统计学评估,并以惊厥后脑电图活动特征阶段的函数形式呈现。发现脑葡萄糖代谢与惊厥后脑电图恢复之间存在相关性。惊厥后脑代谢的恢复在惊厥后状态的前12分钟内是不连续的。在电静息和周期性δ波阶段,脑代谢转向无氧方向。治疗期间,在癫痫发作活动和恢复过程中未发生缺氧性缺氧或酸中毒,可测量的代谢变化适中,推测在治疗“效果”中不起重要作用。