Riala Kaisa, Taanila Anja, Hakko Helinä, Räsänen Pirkko
Department of Psychiatry, Oulu University Hospital, Oulu, Finland.
Ann Epidemiol. 2009 May;19(5):329-35. doi: 10.1016/j.annepidem.2008.12.004. Epub 2009 Feb 20.
We sought to investigate the relationship between regular daily smoking in adolescence and in adulthood, the onset age of suicidal behavior, and the repetitiveness of suicide attempts by the age of 31 years.
Data from the Northern Finland 1966 Birth Cohort (NFBC 1966, n = 7995) were linked with the National Finnish Hospital Discharge registers (FHDR). Smoking habits of the cohort members were assessed at the ages of 14 and 31 years.
After adjusting for hospital-treated psychiatric disorders and several sociodemographic characteristics, women with prolonged smoking from 14 to 31 years especially were at increased hazard (adjusted hazard ratio, 6.67; 95% confidence interval, 3.06-14.52) for having their first suicide attempt at younger age compared with infrequent smokers/nonsmokers. Smoking habits were not associated with the repetitiveness of suicide attempts in either gender.
This study confirms the association between smoking and suicidality. Further studies are needed to investigate the neurobiological basis of this association.
我们试图研究青少年期和成年期的日常规律吸烟、自杀行为的起始年龄以及31岁前自杀未遂的重复性之间的关系。
来自芬兰北部1966年出生队列（NFBC 1966，n = 7995）的数据与芬兰国家医院出院登记册（FHDR）相关联。在队列成员14岁和31岁时评估其吸烟习惯。
在对医院治疗的精神疾病和一些社会人口学特征进行调整后，与偶尔吸烟者/不吸烟者相比，从14岁到31岁长期吸烟的女性尤其在年轻时首次自杀未遂的风险增加（调整后的风险比为6.67；95%置信区间为3.06 - 14.52）。吸烟习惯与任何性别的自杀未遂重复性均无关联。
本研究证实了吸烟与自杀倾向之间的关联。需要进一步研究来调查这种关联的神经生物学基础。
