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青少年时期的运动、吸烟和超重与成年后患坐骨神经痛的关系:一项对出生队列的 28 年随访研究。

Sports, smoking, and overweight during adolescence as predictors of sciatica in adulthood: a 28-year follow-up study of a birth cohort.

机构信息

Finnish Institute of Occupational Health, Aapistie 1, 90220 Oulu, Finland.

出版信息

Am J Epidemiol. 2011 Apr 15;173(8):890-7. doi: 10.1093/aje/kwq459. Epub 2011 Mar 10.

DOI:10.1093/aje/kwq459
PMID:21393341
Abstract

Lifestyle factors such as smoking, obesity, and level of physical activity predict low back pain (LBP) and sciatica. The authors investigated whether participating in sports, smoking, and being overweight or obese at 14 years of age predicted hospitalizations due to LBP or sciatica in adulthood. In 1980, at the age of 14 years, a total of 11,399 members of the 1966 Northern Finland Birth Cohort returned the postal questionnaire. Patients from the 1966 Northern Finland Birth Cohort who were hospitalized because of LBP or sciatica were followed to the end of 2008 through the Finnish Hospital Discharge Register. Data were analyzed using Cox's proportional hazards multistate model with the Markov clock forward time scale. During follow-up, 119 females (2.7%) and 254 males (5.6%) had been hospitalized at least once because of LBP or sciatica. Among females, overweight was associated with an increased risk of second-time hospitalization for surgical treatment for sciatica (hazard ratio = 7.1, 95% confidence interval: 1.5, 34.4). Among males, smoking was associated with an increased risk of first-time nonsurgical hospitalization (hazard ratio = 1.8, 95% confidence interval: 1.2, 2.7) and second-time surgical hospitalization (hazard ratio = 3.2, 95% confidence interval: 1.2, 8.2). The authors found potentially modifiable risk factors in adolescence that predicted hospital treatments for low back disorders during adolescence and young adulthood.

摘要

生活方式因素,如吸烟、肥胖和身体活动水平,可预测腰痛(LBP)和坐骨神经痛。作者研究了在 14 岁时参与运动、吸烟以及超重或肥胖是否会预测成年后患腰痛或坐骨神经痛而住院。1980 年,在 14 岁时,共有 1966 年芬兰北部出生队列的 11399 名成员通过邮寄问卷进行了回复。1966 年芬兰北部出生队列的患者因腰痛或坐骨神经痛住院,通过芬兰住院患者登记系统,随访至 2008 年底。使用 Cox 比例风险多状态模型和 Markov 时钟正向时间尺度对数据进行分析。在随访期间,119 名女性(2.7%)和 254 名男性(5.6%)至少因腰痛或坐骨神经痛住院一次。在女性中,超重与第二次因坐骨神经痛手术治疗而住院的风险增加相关(风险比=7.1,95%置信区间:1.5,34.4)。在男性中,吸烟与首次非手术性住院(风险比=1.8,95%置信区间:1.2,2.7)和第二次手术性住院(风险比=3.2,95%置信区间:1.2,8.2)的风险增加相关。作者发现,青少年时期存在潜在的可改变的危险因素,这些危险因素可预测青少年和年轻成人时期的腰部疾病住院治疗。

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