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急性A型主动脉夹层的手术策略:升主动脉或半弓置换术与带冰冻象鼻的全弓置换术的比较

Operative strategy for acute type a aortic dissection: ascending aortic or hemiarch versus total arch replacement with frozen elephant trunk.

作者信息

Uchida Naomichi, Shibamura Hidenori, Katayama Akira, Shimada Norimitsu, Sutoh Miwa, Ishihara Hiroshi

机构信息

Division of Cardiovascular Surgery, Hiroshima-city Asa General Hospital, Hiroshima, Japan.

出版信息

Ann Thorac Surg. 2009 Mar;87(3):773-7. doi: 10.1016/j.athoracsur.2008.11.061.

Abstract

BACKGROUND

This report compares long-term results with total arch replacement with frozen elephant trunk (FET) to ascending aortic or hemiarch replacement (AHR) for acute type A aortic dissection.

METHODS

The subjects were 120 consecutive patients, including 65 who received FET and 55 who had AHR for acute type A aortic dissection from 1997 to 2008. The late results after surgery were retrospectively compared between the FET and ARH groups.

RESULTS

Three patients in the FET group died, and 2 patients in the AHR group died. In long-term follow-up (mean, 67 months), the survival rate after 5 years was 95.3% for the FET group and 69.0% for the AHR group (p = 0.03). The event rate for the thoracic aorta after 5 years showed a significant difference between the FET and AHR groups (95.7% versus 73.0%, p = 0.01). A false lumen at the proximal descending aorta was patent in 16 patients (29%) in the AHR group, but it was thrombosed in all in the FET group.

CONCLUSIONS

In patients with acute type A aortic dissection, it is possible to perform extensive primary repair using the FET technique with relative safety. FET may reduce the necessity for further operations to manage a residual false lumen.

摘要

背景

本报告比较了采用带冰冻象鼻支架(FET)的全弓置换术与升主动脉或半弓置换术(AHR)治疗急性A型主动脉夹层的长期效果。

方法

研究对象为120例连续患者,其中65例接受FET治疗,55例接受AHR治疗,均为1997年至2008年期间的急性A型主动脉夹层患者。对FET组和AHR组术后的远期结果进行回顾性比较。

结果

FET组有3例患者死亡,AHR组有2例患者死亡。在长期随访(平均67个月)中,FET组5年后的生存率为95.3%,AHR组为69.0%(p = 0.03)。5年后胸主动脉的事件发生率在FET组和AHR组之间存在显著差异(95.7%对73.0%,p = 0.01)。AHR组16例患者(29%)降主动脉近端假腔通畅,而FET组所有患者的假腔均血栓形成。

结论

对于急性A型主动脉夹层患者,采用FET技术进行广泛的一期修复相对安全可行。FET可能减少处理残余假腔所需的进一步手术。

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