Jorgensen Bettina, Olsen Lars Henning, Jorgensen Troels Munch
Institute of Clinical Medicine (BJ) and Department of Urology, Section of Pediatric Urology, Aarhus University Hospital-Skejby, Aarhus, Denmark.
J Urol. 2009 Apr;181(4):1862-7; discussion 1867-8. doi: 10.1016/j.juro.2008.12.001. Epub 2009 Feb 23.
We compared findings from natural fill urodynamics and conventional cystometrogram in infants with neurogenic bladder.
We retrospectively analyzed data from 19 infants undergoing 24-hour natural fill urodynamics and cystometrogram. The infants concurrently underwent ultrasound. Voided volume, detrusor overactivity, area under the curve (per minute) and baseline detrusor pressure obtained at natural fill urodynamics were compared to cystometric capacity, detrusor overactivity, leak point pressures and bladder compliance obtained at cystometrogram.
Voided volumes during natural fill urodynamics were significantly less than cystometric capacity volumes (p <0.001). Natural fill urodynamics revealed more detrusor overactivity than did cystometrogram. Four infants with leak point pressures greater than 40 cm H2O had detrusor overactivity at natural fill urodynamics. Five patients with leak point pressure less than 40 cm H2O had no detrusor overactivity at natural fill urodynamics or cystometrogram. Four of 5 infants with decreased bladder compliance had baseline detrusor pressure greater than 10 cm H2O and detrusor overactivity.
Urodynamic parameters obtained at natural fill urodynamics may be associated with cornerstone parameters such as leak point pressure and bladder compliance obtained at cystometrogram.
我们比较了神经源性膀胱婴儿自然充盈尿动力学检查和传统膀胱测压的结果。
我们回顾性分析了19例接受24小时自然充盈尿动力学检查和膀胱测压的婴儿的数据。这些婴儿同时接受了超声检查。将自然充盈尿动力学检查时获得的排尿量、逼尿肌过度活动、曲线下面积（每分钟）和基线逼尿肌压力与膀胱测压时获得的膀胱容量、逼尿肌过度活动、漏尿点压力和膀胱顺应性进行比较。
自然充盈尿动力学检查期间的排尿量显著低于膀胱测压容量（p<0.001）。自然充盈尿动力学检查显示逼尿肌过度活动比膀胱测压更多。4例漏尿点压力大于40 cm H2O的婴儿在自然充盈尿动力学检查时有逼尿肌过度活动。5例漏尿点压力小于40 cm H2O的患者在自然充盈尿动力学检查或膀胱测压时无逼尿肌过度活动。5例膀胱顺应性降低的婴儿中有4例基线逼尿肌压力大于10 cm H2O且有逼尿肌过度活动。
自然充盈尿动力学检查获得的尿动力学参数可能与膀胱测压时获得的基石参数如漏尿点压力和膀胱顺应性相关。
