Lin Cheng-An J, Yang Ting-Ya, Lee Chih-Hsien, Huang Sherry H, Sperling Ralph A, Zanella Marco, Li Jimmy K, Shen Ji-Lin, Wang Hsueh-Hsiao, Yeh Hung-I, Parak Wolfgang J, Chang Walter H
Department of Biomedical Engineering, Chung Yuan Christian University, Chung-Li 32023, Taiwan, ROC.
ACS Nano. 2009 Feb 24;3(2):395-401. doi: 10.1021/nn800632j.
Synthesis of ultrasmall water-soluble fluorescent gold nanoclusters is reported. The clusters have a decent quantum yield, high colloidal stability, and can be readily conjugated with biological molecules. Specific staining of cells and nonspecific uptake by living cells is demonstrated.
报道了超小水溶性荧光金纳米团簇的合成。这些团簇具有良好的量子产率、高胶体稳定性,并且可以很容易地与生物分子结合。证明了对细胞的特异性染色以及活细胞的非特异性摄取。