Blankenburg M, Hechler T, Dubbel G, Wamsler C, Zernikow B
Vodafone Foundation Institute for Children's Pain Therapy and Paediatric Palliative Care (VIKP), Clinic for Children and Adolescents Datteln, University Witten/Herdecke, Datteln, Germany.
Cephalalgia. 2009 Aug;29(8):873-82. doi: 10.1111/j.1468-2982.2008.01813.x. Epub 2009 Feb 19.
Whereas paroxysmal hemicrania (PH) is studied extensively in adults, even case reports of PH in children are rare. We present the first prospective follow-up study on PH in children. Our aim was to investigate whether differences exist between paediatric and adult patients. We assessed all children with chronic headache who were referred to our paediatric out-patient pain clinic within 3 years based on interviews and validated questionnaires. Among 628 patients we found five children with PH (0.8%) and three with probable PH (0.5%), in total 1.3%. Pain characteristics, autonomic symptoms and treatment response to indomethacin were similar to adult PH patients. Our results demonstrate that the International Headache Society classification of PH is also applicable to children. We suspect that PH has been underdiagnosed in children and therefore suboptimally treated thus far.
虽然成人发作性偏侧头痛（PH）已得到广泛研究，但儿童PH的病例报告却很罕见。我们开展了第一项关于儿童PH的前瞻性随访研究。我们的目的是调查儿童患者与成人患者之间是否存在差异。我们根据访谈和经过验证的问卷，对3年内转诊至我们儿科门诊疼痛诊所的所有慢性头痛儿童进行了评估。在628例患者中，我们发现5例儿童患有PH（0.8%），3例可能患有PH（0.5%），总计1.3%。疼痛特征、自主神经症状以及对吲哚美辛的治疗反应与成人PH患者相似。我们的结果表明，国际头痛协会对PH的分类也适用于儿童。我们怀疑PH在儿童中一直未得到充分诊断，因此迄今为止治疗效果欠佳。
