De Reuck J, Van Maele G, Cordonnier C, Leys D
Department of Neurology, University Hospital, Ghent, Belgium.
Acta Neurol Belg. 2008 Dec;108(4):135-8.
Partial anterior circulation syndrome (PACS), due to cerebral infarction, is the most common stroke presentation of patients with seizures. This study investigates the characteristics of such patients according to their seizure onset time.
The characteristics of 151 patients with a PACS and seizures were compared to 310 without seizures. The seizure groups were classified as those of early- (EO), of late- (LO) and of very late-onset (VLO) and those due to recurrent infarcts (RI).
Temporal lobe infarction is the main risk factor for developing seizures (P < 0.02). Seizures are responsible for increased dependency except in patients with those of VLO (P < 0.03). Patients with EO seizures have the worse outcome (P = 0.0111) with a trend of more status epilepticus (P = 0.066) but less recurrence (P = 0.003). A cardiac-embolic source is more common in patients with seizures due to RI (P = 0.015). Post-ictal EEG patterns are significantly different from those in the patients without seizures (P < 0.001) except for seizures of VLO.
There are significant differences in the seizure characteristics according to their time of onset.
因脑梗死导致的部分前循环综合征（PACS）是癫痫患者最常见的卒中表现形式。本研究根据癫痫发作时间调查此类患者的特征。
将151例患有PACS且伴有癫痫发作的患者的特征与310例无癫痫发作的患者进行比较。癫痫发作组分为早发性（EO）、晚发性（LO）、极晚发性（VLO）以及复发性梗死（RI）所致癫痫发作组。
颞叶梗死是发生癫痫的主要危险因素（P < 0.02）。癫痫发作会导致依赖增加，但VLO患者除外（P < 0.03）。EO癫痫发作患者的预后最差（P = 0.0111），癫痫持续状态的趋势更明显（P = 0.066），但复发较少（P = 0.003）。RI所致癫痫发作患者中心源性栓塞源更为常见（P = 0.015）。除VLO癫痫发作外，发作后脑电图模式与无癫痫发作患者的脑电图模式有显著差异（P < 0.001）。
根据癫痫发作时间不同，癫痫发作特征存在显著差异。
