Yatabe Yoshihisa, Miyakawa Shumpei, Ohmori Hajime, Mishima Hajime, Adachi Takako
Department of Orthopaedic Surgery, Moriya Daiichi Hospital, Japan.
Adv Exp Med Biol. 2009;643:245-52. doi: 10.1007/978-0-387-75681-3_25.
Taurine concentration in rat skeletal muscles after endurance running, with and without taurine administration was studied. Taurine concentrations in skeletal muscles was significantly decreased in exercised groups without taurine administration. However, taurine administration reduced the decrease of taurine concentration in skeletal muscles in exercise. Oral administration of taurine has effect for maintaining taurine concentration in skeletal muscles in exercise. The duration of running time to exhaustion of rats, with and without taurine administration were studied. The duration of running time to exhaustion was significantly increased by taurine administration. Oral administration of taurine increases the ability of physical endurance. Rat urinary excretions of creatinine, creatine, 3-methylhistidine (3-MH) after treadmill running, with and without taurine administration were studied. Rat urinary excretions of creatinine, creatine, 3-MH after treadmill running was significantly decreased with taurine administration. Taurine administration was considered to reduce the exercise-induced muscle fatigue.
研究了耐力跑后大鼠骨骼肌中的牛磺酸浓度，以及给予和未给予牛磺酸的情况。在未给予牛磺酸的运动组中，骨骼肌中的牛磺酸浓度显著降低。然而，给予牛磺酸可减少运动时骨骼肌中牛磺酸浓度的下降。口服牛磺酸对维持运动时骨骼肌中的牛磺酸浓度有作用。研究了给予和未给予牛磺酸的大鼠力竭跑步时间。给予牛磺酸显著增加了力竭跑步时间。口服牛磺酸可提高身体耐力。研究了给予和未给予牛磺酸的大鼠在跑步机跑步后尿中肌酐、肌酸、3-甲基组氨酸（3-MH）的排泄情况。给予牛磺酸后，跑步机跑步后大鼠尿中肌酐、肌酸、3-MH的排泄显著减少。给予牛磺酸被认为可减轻运动引起的肌肉疲劳。
