来自蕨类植物毛柄耳蕨的杀螺间苯三酚类化合物。

Molluscicidal Phloroglucinols from the Fern Elaphoglossum piloselloides.

作者信息

Socolsky Cecilia, Borkosky Susana A, Asakawa Yoshinori, Bardón Alicia

机构信息

Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Tucumán, Argentina.

出版信息

J Nat Prod. 2009 Apr;72(4):787-90. doi: 10.1021/np800724h.

DOI:10.1021/np800724h

PMID:19239238

Abstract

Two new bicyclic phloroglucinols were isolated from the diethyl ether extract of an Argentine collection of the fern Elaphoglossum piloselloides. Structures were established by analysis of their spectroscopic data ((1)H NMR, HRMS, IR) and chemical derivatization. Both compounds show an acute molluscicidal activity against the schistosomiasis vector snail Biomphalaria peregrina.

摘要

从阿根廷采集的毛叶舌蕨的乙醚提取物中分离出两种新的双环间苯三酚。通过对其光谱数据（核磁共振氢谱、高分辨质谱、红外光谱）的分析和化学衍生化确定了结构。这两种化合物对血吸虫病传播媒介蜗牛——奇异 Biomphalaria 螺均表现出急性杀螺活性。