Hsu Chi-Shiung, Hsu Chia-Chen, Wang Jun-Wen, Lin Po-Chun
Department of Orthopedic Surgery, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chang Gung Med J. 2008 Nov-Dec;31(6):583-91.
Static antibiotic-impregnated cement spacers have been used widely to treat chronically infected total knee arthroplasties with a high success result. However, difficulty in surgical exposure during revision has been encountered. The purpose of this study was to evaluate the clinical results of two-stage reimplantation of an infected total knee arthroplasty using a static antibiotic-impregnated cement spacer.
Thirty-one patients (32 knees) with infected total knee arthroplasty had a two-stage reimplantation using a static antibiotic-impregnated cement spacer. Twelve (37.5%) of 32 knees required a V-Y quadricepsplasty and five (15.6%) required a quadriceps snip for surgical exposure at revision. One patient was lost to follow-up and three patients died of unrelated causes. The remaining 27 patients (28 knees) returned at a mean of 68.3 months (8-197 months) for clinical evaluation.
Four knees (14%) had recurrent infection. The mean Knee Society score improved from 40 points preoperatively to 82 points postoperatively. The mean functional score improved from 10 points preoperatively to 60 points postoperatively. The mean range of knee motion improved from 57 degrees preoperatively to 88 degrees at the latest follow-up. Three knees with V-Y quadricepsplasty developed an extension lag from 20 degrees to 45 degrees and three knees had a patella baja postoperatively.
Two-stage reimplantation of an infected total knee arthroplasty using a static antibiotic-cement spacer achieved an infection control rate of 86% and improvement in the clinical results. However, weakness of the extensor mechanism of the knee associated with a V-Y quadricepsplasty, which was required in a high percentage of patients during revision surgery in our
静态抗生素骨水泥间隔物已被广泛用于治疗慢性感染的全膝关节置换术,成功率较高。然而,翻修手术中手术暴露存在困难。本研究的目的是评估使用静态抗生素骨水泥间隔物进行感染性全膝关节置换术两阶段再植入的临床结果。
31例(32膝)感染性全膝关节置换术患者使用静态抗生素骨水泥间隔物进行两阶段再植入。32膝中有12膝(37.5%)需要进行V-Y股四头肌成形术,5膝(15.6%)需要进行股四头肌切断术以在翻修时进行手术暴露。1例患者失访,3例患者死于无关原因。其余27例患者(28膝)平均在68.3个月(8 - 197个月)后返回进行临床评估。
4膝(14%)出现复发性感染。膝关节协会平均评分从术前的40分提高到术后的82分。平均功能评分从术前的10分提高到术后的60分。膝关节平均活动范围从术前的57度提高到最近随访时的88度。3例行V-Y股四头肌成形术的膝关节出现20度至45度的伸直滞后,3膝术后出现低位髌骨。
使用静态抗生素骨水泥间隔物进行感染性全膝关节置换术的两阶段再植入实现了86%的感染控制率,并改善了临床结果。然而,V-Y股四头肌成形术相关的膝关节伸肌机制无力,在我们的翻修手术中,高比例患者需要这种手术。