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无菌性与二期感染性膝关节翻修术的直接住院护理成本比较分析

Comparative Analysis of Direct Hospital Care Costs between Aseptic and Two-Stage Septic Knee Revision.

作者信息

Kasch Richard, Merk Sebastian, Assmann Grit, Lahm Andreas, Napp Matthias, Merk Harry, Flessa Steffen

机构信息

Center for Orthopedics, Trauma Surgery and Rehabilitation Medicine, Clinic and Outpatient Clinic for Orthopedics and Orthopedic Surgery, University Medicine Greifswald, Greifswald, Germany.

Kliniken Maria Hilf Mönchengladbach, Academic Teaching Hospital of the RWTH Aachen, Mönchengladbach, Germany.

出版信息

PLoS One. 2017 Jan 20;12(1):e0169558. doi: 10.1371/journal.pone.0169558. eCollection 2017.

Abstract

BACKGROUND

The most common intermediate and long-term complications of total knee arthroplasty (TKA) include aseptic and septic failure of prosthetic joints. These complications cause suffering, and their management is expensive. In the future the number of revision TKA will increase, which involves a greater financial burden. Little concrete data about direct costs for aseptic and two-stage septic knee revisions with an in depth-analysis of septic explantation and implantation is available.

QUESTIONS/PURPOSES: A retrospective consecutive analysis of the major partial costs involved in revision TKA for aseptic and septic failure was undertaken to compare 1) demographic and clinical characteristics, and 2) variable direct costs (from a hospital department's perspective) between patients who underwent single-stage aseptic and two-stage septic revision of TKA in a hospital providing maximum care. We separately analyze the explantation and implantation procedures in septic revision cases and identify the major cost drivers of knee revision operations.

METHODS

A total of 106 consecutive patients (71 aseptic and 35 septic) was included. All direct costs of diagnosis, surgery, and treatment from the hospital department's perspective were calculated as real purchase prices. Personnel involvement was calculated in units of minutes.

RESULTS

Aseptic versus septic revisions differed significantly in terms of length of hospital stay (15.2 vs. 39.9 days), number of reported secondary diagnoses (6.3 vs. 9.8) and incision-suture time (108.3 min vs. 193.2 min). The management of septic revision TKA was significantly more expensive than that of aseptic failure ($12,223.79 vs. $6,749.43) (p <.001). On the level of the separate hospitalizations the mean direct costs of explantation stage ($4,540.46) were lower than aseptic revision TKA ($6,749.43) which were again lower than those of the septic implantation stage ($7,683.33). All mean costs of stays were not comparable as they differ significantly (p <.001). Major cost drivers were the cost of the implant and general staff. The septic implantation part was on average $3,142.87 more expensive than septic explantations (p <.001).

CONCLUSIONS

Our study for the first time provides a detailed analysis of the major direct case costs of aseptic and septic revision TKA from the hospital-department's perspective which is the basis for long-term orientated decision making. In the future, our cost analysis has to be interpreted in relation to reimbursement estimates. This is important to check whether revision TKA lead to a financial loss for the operating department.

摘要

背景

全膝关节置换术(TKA)最常见的中远期并发症包括假体关节的无菌性和感染性失败。这些并发症给患者带来痛苦,且治疗费用高昂。未来,翻修TKA的数量将会增加,这将带来更大的经济负担。目前关于无菌性和两阶段感染性膝关节翻修的直接成本,以及对感染性取出和植入进行深入分析的具体数据较少。

问题/目的:对无菌性和感染性失败的TKA翻修所涉及的主要部分成本进行回顾性连续分析,以比较1)人口统计学和临床特征,以及2)在一家提供最高级护理的医院中,接受单阶段无菌性和两阶段感染性TKA翻修的患者之间的可变直接成本(从医院科室角度)。我们分别分析感染性翻修病例中的取出和植入手术,并确定膝关节翻修手术的主要成本驱动因素。

方法

共纳入106例连续患者(71例无菌性和35例感染性)。从医院科室角度计算诊断、手术和治疗的所有直接成本,以实际采购价格为准。人员参与时间以分钟为单位计算。

结果

无菌性翻修与感染性翻修在住院时间(15.2天对39.9天)、报告的次要诊断数量(6.3对9.8)和切口缝合时间(108.3分钟对193.2分钟)方面存在显著差异。感染性TKA翻修的治疗费用明显高于无菌性失败(12,223.79美元对6,749.43美元)(p <.001)。在单独住院层面,取出阶段的平均直接成本(4,540.46美元)低于无菌性TKA翻修(6,749.43美元),而无菌性TKA翻修又低于感染性植入阶段(7,683.33美元)。所有住院的平均成本不可比,因为它们差异显著(p <.001)。主要成本驱动因素是植入物成本和普通 staff成本。感染性植入部分平均比感染性取出贵3,142.87美元(p <.001)。

结论

我们的研究首次从医院科室角度对无菌性和感染性TKA翻修的主要直接病例成本进行了详细分析,这是长期导向决策的基础。未来,我们的成本分析必须结合报销估算进行解读。这对于检查TKA翻修是否会给手术科室带来经济损失很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca4/5249079/d06b8959c936/pone.0169558.g001.jpg

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