Park Hyun Seok, Kwon Soon Chan, Kim Min-Ho, Park Eun Suk, Sim Hong Bo, Lyo In Uk
Department of Neurosurgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Neurointervention. 2013 Sep;8(2):87-91. doi: 10.5469/neuroint.2013.8.2.87. Epub 2013 Aug 29.
This study is an overview of the clinical and angiographic outcomes of patients who undergo treatment for distal anterior cerebral artery aneurysms.
Between January 2009 and March 2012, 444 cerebral aneurysms were treated using endovascular coil embolization at our institute. Among them, 217 aneurysms were followed-up with angiography at least six months later. Of these, there were 16 distal anterior cerebral artery (ACA) aneurysms in 16 patients. We conducted a retrospective review of clinical and radiological follow-up results of all patients with distal ACA aneurysms. The clinical and angiographic outcomes were assessed using the modified Rankin scale (mRS) and the Raymond classification scale, respectively.
The mean age was 54.7 ± 10.2 years (41-75 years). The mean follow-up period was 20.6 ± 9.64 months (6-37 months). Three patients presented with acute rupture. The average aneurysm size was 4.98 ± 1.39 mm (3.0-8.1 mm), and eight of 16 aneurysms (50%) had aspect ratios < 2.0. All 16 patients presented with complete obliteration immediately after the procedure. However, two patients had procedure-related complications, one with coil extrusion to the subarachnoid space without hemorrhage and one with thromboembolism subsequent to chemical thrombolysis. In the follow-up angiography, one major and five minor recurrences (for a total of six recurrences, 37.5%) were detected. However, the differences between the ACA aneurysm group and others were not statistically significant. Clinical outcomes were good for all of the patients at the time of discharge (mean mRS: 0.25, 0 to 1) and at the follow-ups (mean mRS: 0).
Despite a comparatively high recurrence rate, the endovascular treatment of distal anterior cerebral aneurysms is feasible and has a good clinical outcome.
本研究是对接受远端大脑前动脉动脉瘤治疗患者的临床和血管造影结果的概述。
2009年1月至2012年3月期间,我院使用血管内弹簧圈栓塞治疗了444例脑动脉瘤。其中,217例动脉瘤至少在六个月后接受了血管造影随访。其中,16例患者有16个远端大脑前动脉(ACA)动脉瘤。我们对所有远端ACA动脉瘤患者的临床和放射学随访结果进行了回顾性分析。分别使用改良Rankin量表(mRS)和Raymond分类量表评估临床和血管造影结果。
平均年龄为54.7±10.2岁(41 - 75岁)。平均随访期为20.6±9.64个月(6 - 37个月)。3例患者出现急性破裂。动脉瘤平均大小为4.98±1.39毫米(3.0 - 8.1毫米),16个动脉瘤中有8个(50%)长宽比<2.0。所有16例患者术后均立即实现完全闭塞。然而,2例患者出现了与手术相关的并发症,1例弹簧圈挤入蛛网膜下腔但未出血,1例在化学溶栓后出现血栓栓塞。在随访血管造影中,检测到1例主要复发和5例次要复发(共6例复发,37.5%)。然而,ACA动脉瘤组与其他组之间的差异无统计学意义。所有患者出院时(平均mRS:0.25,0至1)及随访时(平均mRS:0)临床结果均良好。
尽管复发率相对较高,但远端大脑前动脉瘤的血管内治疗是可行的,且临床结果良好。