Lim Jae Joon, Kim Sang Hyun, Cho Ki Hong, Yoon Do Heum, Kim Se Hoon
Department of Neurosurgery, Ajou University School of Medicine, Suwon, Korea.
J Korean Neurosurg Soc. 2009 Jan;45(1):35-8. doi: 10.3340/jkns.2009.45.1.35. Epub 2009 Jan 31.
We present a patient with multifocal symptomatic osseous chordomas having unusual growth patterns with review of the pertinent literature. The patient was 62-year-old male and had multiple osseous chordomas located in sacral, thoracic, and paraclival jugular foramen areas. There was no metastasis in other organs. All affected sites were osseous. The multicentric chordomas are extremely rare. This case could be considered as a chordoma involving multiple neuraxial bones. But, the possibility of multicentricity could also be thought. In such cases radical resection should be performed for each lesion at the initial diagnosis. If complete surgical resections are infeasible or impossible, preoperative or postoperative radiation therapy should be planned for the highest possibility of successful treatment.
我们报告一例患有多灶性症状性骨脊索瘤且生长模式异常的患者,并对相关文献进行回顾。该患者为62岁男性,在骶骨、胸椎和岩斜区颈静脉孔区域有多发骨脊索瘤。其他器官无转移。所有受累部位均为骨性。多中心性脊索瘤极为罕见。该病例可被视为累及多个神经轴骨的脊索瘤。但是,也应考虑多中心性的可能性。在这种情况下,初次诊断时应对每个病灶进行根治性切除。如果完全手术切除不可行或不可能,则应计划术前或术后放疗,以获得最高的成功治疗可能性。